Scott A. Coonrod Department of Baker Institute for Animal Health Cornell University Biography Publications Institution JoVE Articles Scott A. Coonrod has not added a biography. If you are Scott A. Coonrod and would like to personalize this page please email our Author Liaison for assistance. Publications Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design ACS Chemical Biology. Apr, 2015 | Pubmed ID: 25621824 Design, Synthesis, and Biological Evaluation of Tetrazole Analogs of Cl-amidine As Protein Arginine Deiminase Inhibitors Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25559347 PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia Cancer Research. Nov, 2014 | Pubmed ID: 25213324 Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure PLoS Genetics. Sep, 2014 | Pubmed ID: 25211228 Transient Estrogen Receptor Binding and P300 Redistribution Support a Squelching Mechanism for Estradiol-repressed Genes Molecular Endocrinology (Baltimore, Md.). Sep, 2014 | Pubmed ID: 25051172 A Novel Role for Protein Arginine Deiminase 4 in Pluripotency: the Emerging Role of Citrullinated Histone H1 in Cellular Programming BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Aug, 2014 | Pubmed ID: 24889365 The Role of MATER in Endoplasmic Reticulum Distribution and Calcium Homeostasis in Mouse Oocytes Developmental Biology. Feb, 2014 | Pubmed ID: 24374158 Dysregulation of PAD4-mediated Citrullination of Nuclear GSK3β Activates TGF-β Signaling and Induces Epithelial-to-mesenchymal Transition in Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23818587 Identification of Macrophage Extracellular Trap-like Structures in Mammary Gland Adipose Tissue: a Preliminary Study Frontiers in Immunology. 2013 | Pubmed ID: 23508122 D-amino Acid Based Protein Arginine Deiminase Inhibitors: Synthesis, Pharmacokinetics, and in Cellulo Efficacy ACS Medicinal Chemistry Letters. Oct, 2012 | Pubmed ID: 23420624 Identification of PADI2 As a Potential Breast Cancer Biomarker and Therapeutic Target BMC Cancer. 2012 | Pubmed ID: 23110523 Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis Biochemistry Research International. 2012 | Pubmed ID: 23019525 Potential Role for PAD2 in Gene Regulation in Breast Cancer Cells PloS One. 2012 | Pubmed ID: 22911765 Peptidylarginine Deiminase 2-catalyzed Histone H3 Arginine 26 Citrullination Facilitates Estrogen Receptor α Target Gene Activation Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22853951 Role for Peptidylarginine Deiminase Enzymes in Disease and Female Reproduction The Journal of Reproduction and Development. 2012 | Pubmed ID: 22790870 Potential Role for PADI-mediated Histone Citrullination in Preimplantation Development BMC Developmental Biology. 2012 | Pubmed ID: 22712504 Synthesis and Screening of a Haloacetamidine Containing Library to Identify PAD4 Selective Inhibitors ACS Chemical Biology. Jan, 2012 | Pubmed ID: 22004374 Genome-wide Analysis Reveals PADI4 Cooperates with Elk-1 to Activate C-Fos Expression in Breast Cancer Cells PLoS Genetics. Jun, 2011 | Pubmed ID: 21655091 Regulation of Mouse Oocyte Microtubule and Organelle Dynamics by PADI6 and the Cytoplasmic Lattices Developmental Biology. Feb, 2011 | Pubmed ID: 21147087 Potential Role for MATER in Cytoplasmic Lattice Formation in Murine Oocytes PloS One. 2010 | Pubmed ID: 20830304 Potential Role for Peptidylarginine Deiminase 2 (PAD2) in Citrullination of Canine Mammary Epithelial Cell Histones PloS One. 2010 | Pubmed ID: 20668670 Use of Proteomics to Identify Highly Abundant Maternal Factors That Drive the Egg-to-embryo Transition Reproduction (Cambridge, England). May, 2010 | Pubmed ID: 20106898 Histone Hypercitrullination Mediates Chromatin Decondensation and Neutrophil Extracellular Trap Formation The Journal of Cell Biology. Jan, 2009 | Pubmed ID: 19153223 Role for PADI6 and the Cytoplasmic Lattices in Ribosomal Storage in Oocytes and Translational Control in the Early Mouse Embryo Development (Cambridge, England). Aug, 2008 | Pubmed ID: 18599511 Antibodies to Two ZP3 B Cell Epitopes Affect Zona Pellucida Assembly Journal of Reproductive Immunology. Jul, 2008 | Pubmed ID: 18420282 Peptidylarginine Peptidilico (PAD) è Una Proteina Di Granuli Corticali Del Mouse Che Gioca Un Ruolo Nello Sviluppo Embrionale Preimpianto Reproductive Biology and Endocrinology : RB&E. 2005 | Pubmed ID: 16137333 Mouse SLLP1, a Sperm Lysozyme-like Protein Involved in Sperm-egg Binding and Fertilization Developmental Biology. Aug, 2005 | Pubmed ID: 15982649 Regulation of Coactivator Complex Assembly and Function by Protein Arginine Methylation and Demethylimination Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15731352 Human PAD4 Regulates Histone Arginine Methylation Levels Via Demethylimination Science (New York, N.Y.). Oct, 2004 | Pubmed ID: 15345777 Dynamic Alterations of Specific Histone Modifications During Early Murine Development Journal of Cell Science. Sep, 2004 | Pubmed ID: 15316069 Structural Requirements for the Inhibitory Action of the CD9 Large Extracellular Domain in Sperm/oocyte Binding and Fusion Biochemical and Biophysical Research Communications. Nov, 2003 | Pubmed ID: 14575715 SAMP14, a Novel, Acrosomal Membrane-associated, Glycosylphosphatidylinositol-anchored Member of the Ly-6/urokinase-type Plasminogen Activator Receptor Superfamily with a Role in Sperm-egg Interaction The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12788941 EPAD, an Oocyte and Early Embryo-abundant Peptidylarginine Deiminase-like Protein That Localizes to Egg Cytoplasmic Sheets Developmental Biology. Apr, 2003 | Pubmed ID: 12654293 Oolemmal Proteomics--identification of Highly Abundant Heat Shock Proteins and Molecular Chaperones in the Mature Mouse Egg and Their Localization on the Plasma Membrane Reproductive Biology and Endocrinology : RB&E. Feb, 2003 | Pubmed ID: 12646049 SLLP1, a Unique, Intra-acrosomal, Non-bacteriolytic, C Lysozyme-like Protein of Human Spermatozoa Biology of Reproduction. May, 2003 | Pubmed ID: 12606493 TACC3 Expression and Localization in the Murine Egg and Ovary Molecular Reproduction and Development. Nov, 2002 | Pubmed ID: 12237944 CABYR, a Novel Calcium-binding Tyrosine Phosphorylation-regulated Fibrous Sheath Protein Involved in Capacitation Developmental Biology. Feb, 2002 | Pubmed ID: 11820818 Oolemmal Proteomics Journal of Reproductive Immunology. Jan, 2002 | Pubmed ID: 11730904 Utilizzo del saggio soft Agar Colony Formazione per identificare inibitori di tumorigenicità in cellule di carcinoma mammario Sachi Horibata1, Tommy V. Vo2, Venkataraman Subramanian3, Paul R. Thompson3, Scott A. Coonrod1 1Department of Baker Institute for Animal Health, Cornell University, 2Department of Molecular Biology and Genetics, Cornell University, 3Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School Medicine
Utilizzo del saggio soft Agar Colony Formazione per identificare inibitori di tumorigenicità in cellule di carcinoma mammario Sachi Horibata1, Tommy V. Vo2, Venkataraman Subramanian3, Paul R. Thompson3, Scott A. Coonrod1 1Department of Baker Institute for Animal Health, Cornell University, 2Department of Molecular Biology and Genetics, Cornell University, 3Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School Medicine