Shaun R. Coughlin Cardiovascular Research Institute University of California, San Francisco Biography Publications Institution JoVE Articles Shaun R. Coughlin has not added a biography. If you are Shaun R. Coughlin and would like to personalize this page please email our Author Liaison for assistance. Publications Gαi/o-coupled Receptor Signaling Restricts Pancreatic β-cell Expansion Proceedings of the National Academy of Sciences of the United States of America. Mar, 2015 | Pubmed ID: 25695968 Redundancy and Interaction of Thrombin- and Collagen-mediated Platelet Activation in Tail Bleeding and Carotid Thrombosis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2014 | Pubmed ID: 25278288 Podoplanin Maintains High Endothelial Venule Integrity by Interacting with Platelet CLEC-2 Nature. Oct, 2013 | Pubmed ID: 23995678 IL-7 Production in Murine Lymphatic Endothelial Cells and Induction in the Setting of Peripheral Lymphopenia International Immunology. Aug, 2013 | Pubmed ID: 23657000 PAR1 Contributes to Influenza A Virus Pathogenicity in Mice The Journal of Clinical Investigation. Jan, 2013 | Pubmed ID: 23202729 High-resolution Crystal Structure of Human Protease-activated Receptor 1 Nature. Dec, 2012 | Pubmed ID: 23222541 TMEM16F Forms a Ca2+-activated Cation Channel Required for Lipid Scrambling in Platelets During Blood Coagulation Cell. Sep, 2012 | Pubmed ID: 23021219 Wnt/β-catenin Signaling is Differentially Regulated by Gα Proteins and Contributes to Fibrous Dysplasia Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22106277 Carcinoma Mucins Trigger Reciprocal Activation of Platelets and Neutrophils in a Murine Model of Trousseau Syndrome Blood. Oct, 2011 | Pubmed ID: 21860019 The Sphingosine 1-phosphate Receptor S1P₂ Maintains the Homeostasis of Germinal Center B Cells and Promotes Niche Confinement Nature Immunology. Jul, 2011 | Pubmed ID: 21642988 PAR2 Absence Completely Rescues Inflammation and Ichthyosis Caused by Altered CAP1/Prss8 Expression in Mouse Skin Nature Communications. Jan, 2011 | Pubmed ID: 21245842 Roles and Interactions Among Protease-activated Receptors and P2ry12 in Hemostasis and Thrombosis Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20930120 Identifying Patients at High Risk of a Cardiovascular Event in the Near Future: Current Status and Future Directions: Report of a National Heart, Lung, and Blood Institute Working Group Circulation. Mar, 2010 | Pubmed ID: 20351302 Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo Developmental Cell. Jan, 2010 | Pubmed ID: 20152175 Lymphatic Endothelial Cell Sphingosine Kinase Activity is Required for Lymphocyte Egress and Lymphatic Patterning The Journal of Experimental Medicine. Jan, 2010 | Pubmed ID: 20026661 Sphingosine-1-phosphate in the Plasma Compartment Regulates Basal and Inflammation-induced Vascular Leak in Mice The Journal of Clinical Investigation. Jul, 2009 | Pubmed ID: 19603543 Identification of a Transient Subpial Neurogenic Zone in the Developing Dentate Gyrus and Its Regulation by Cxcl12 and Reelin Signaling Development (Cambridge, England). Jan, 2009 | Pubmed ID: 19103804 Anatomical Profiling of G Protein-coupled Receptor Expression Cell. Oct, 2008 | Pubmed ID: 18984166 Maternal Par4 and Platelets Contribute to Defective Placenta Formation in Mouse Embryos Lacking Thrombomodulin Blood. Aug, 2008 | Pubmed ID: 18490515 A Critical Role for Extracellular Protein Disulfide Isomerase During Thrombus Formation in Mice The Journal of Clinical Investigation. Mar, 2008 | Pubmed ID: 18292814 Probing Cell Type-specific Functions of Gi in Vivo Identifies GPCR Regulators of Insulin Secretion The Journal of Clinical Investigation. Dec, 2007 | Pubmed ID: 17992256 Protease-activated Receptor 2, Dipeptidyl Peptidase I, and Proteases Mediate Clostridium Difficile Toxin A Enteritis Gastroenterology. Jun, 2007 | Pubmed ID: 17570216 Fetal Gene Defects Precipitate Platelet-mediated Pregnancy Failure in Factor V Leiden Mothers The Journal of Experimental Medicine. May, 2007 | Pubmed ID: 17438064 Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-phosphate Science (New York, N.Y.). Apr, 2007 | Pubmed ID: 17363629 Par4 is Required for Platelet Thrombus Propagation but Not Fibrin Generation in a Mouse Model of Thrombosis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17190826 Roles of Protease-activated Receptors in a Mouse Model of Endotoxemia Blood. May, 2006 | Pubmed ID: 16434493 Protease-activated Receptor-2 Activation Induces Acute Lung Inflammation by Neuropeptide-dependent Mechanisms Journal of Immunology (Baltimore, Md. : 1950). Aug, 2005 | Pubmed ID: 16081834 Essential Role for Galpha13 in Endothelial Cells During Embryonic Development Proceedings of the National Academy of Sciences of the United States of America. Jun, 2005 | Pubmed ID: 15919816 PAR1 Cleavage and Signaling in Response to Activated Protein C and Thrombin The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15665002 Platelets, Protease-activated Receptors, and Fibrinogen in Hematogenous Metastasis Blood. Jul, 2004 | Pubmed ID: 15031212 Regulated Shedding of PAR1 N-terminal Exodomain from Endothelial Cells The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14982936 Combined Deficiency of Protease-activated Receptor-4 and Fibrinogen Recapitulates the Hemostatic Defect but Not the Embryonic Lethality of Prothrombin Deficiency Blood. Jan, 2004 | Pubmed ID: 14504091 Protease-activated Receptors 1 and 4 Mediate Thrombin Signaling in Endothelial Cells Blood. Nov, 2003 | Pubmed ID: 12869501 The Rho Guanine Nucleotide Exchange Factor Lsc Homo-oligomerizes and is Negatively Regulated Through Domains in Its Carboxyl Terminus That Are Absent in Novel Splenic Isoforms The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12773540 PARticipation in Inflammation The Journal of Clinical Investigation. Jan, 2003 | Pubmed ID: 12511583 Overview of the Alliance for Cellular Signaling Nature. Dec, 2002 | Pubmed ID: 12478301 Protection Against Thrombosis in Mice Lacking PAR3 Blood. Nov, 2002 | Pubmed ID: 12384423 Genetic Evidence That Protease-activated Receptors Mediate Factor Xa Signaling in Endothelial Cells The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11850418 Анализ кардиомиоцитов развития с помощью иммунофлюоресценции в эмбриональных мыши Сердце Lisa D. Wilsbacher1,2, Shaun R. Coughlin2 1Feinberg Cardiovascular Research Institute, Northwestern University, 2Cardiovascular Research Institute, University of California, San Francisco Developmental Biology Механическая судно Травмы у эмбрионов данио рерио Hilary Clay1, Shaun R. Coughlin1 1Cardiovascular Research Institute, University of California Developmental Biology
Анализ кардиомиоцитов развития с помощью иммунофлюоресценции в эмбриональных мыши Сердце Lisa D. Wilsbacher1,2, Shaun R. Coughlin2 1Feinberg Cardiovascular Research Institute, Northwestern University, 2Cardiovascular Research Institute, University of California, San Francisco Developmental Biology
Механическая судно Травмы у эмбрионов данио рерио Hilary Clay1, Shaun R. Coughlin1 1Cardiovascular Research Institute, University of California Developmental Biology