Silvia C. Finnemann Department of Biological Sciences, Center for Cancer, Genetic Diseases and Gene Regulation Fordham University Biography Publications Institution JoVE Articles Silvia C. Finnemann has not added a biography. If you are Silvia C. Finnemann and would like to personalize this page please email our Author Liaison for assistance. Publications Understanding Photoreceptor Outer Segment Phagocytosis: Use and Utility of RPE Cells in Culture Experimental Eye Research. Sep, 2014 | Pubmed ID: 24780752 Lack of Effect of Microfilament or Microtubule Cytoskeleton-disrupting Agents on Restriction of Externalized Phosphatidylserine to Rod Photoreceptor Outer Segment Tips Advances in Experimental Medicine and Biology. 2014 | Pubmed ID: 24664685 Independent Roles of Methionine Sulfoxide Reductase A in Mitochondrial ATP Synthesis and As Antioxidant in Retinal Pigment Epithelial Cells Free Radical Biology & Medicine. Dec, 2013 | Pubmed ID: 24120970 PI 3-kinase Independent Role for AKT in F-actin Regulation During Outer Segment Phagocytosis by RPE Cells Experimental Eye Research. Aug, 2013 | Pubmed ID: 23669303 Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23150376 Analysis of Photoreceptor Rod Outer Segment Phagocytosis by RPE Cells in Situ Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23150373 Diurnal, Localized Exposure of Phosphatidylserine by Rod Outer Segment Tips in Wild-type but Not Itgb5-/- or Mfge8-/- Mouse Retina Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22566632 Retinal Pigment Epithelial Cells Use a MerTK-dependent Mechanism to Limit the Phagocytic Particle Binding Activity of αvβ5 Integrin Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jan, 2012 | Pubmed ID: 22289110 Essential Diurnal Rac1 Activation During Retinal Phagocytosis Requires αvβ5 Integrin but Not Tyrosine Kinases Focal Adhesion Kinase or Mer Tyrosine Kinase Molecular Biology of the Cell. Mar, 2012 | Pubmed ID: 22262456 αvβ5 Integrin-dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells is Independent of the Integrin Coreceptor Transglutaminase-2 Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183400 Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE in Vivo and in Culture Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183397 Dietary Antioxidants Prevent Age-related Retinal Pigment Epithelium Actin Damage and Blindness in Mice Lacking αvβ5 Integrin Free Radical Biology & Medicine. Feb, 2012 | Pubmed ID: 22178979 Neural Retina and MerTK-independent Apical Polarity of Alphavbeta5 Integrin Receptors in the Retinal Pigment Epithelium Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20238010 The Age Lipid A2E and Mitochondrial Dysfunction Synergistically Impair Phagocytosis by Retinal Pigment Epithelial Cells The Journal of Biological Chemistry. Sep, 2008 | Pubmed ID: 18621729 Lack of Alphavbeta5 Integrin Receptor or Its Ligand MFG-E8: Distinct Effects on Retinal Function Ophthalmic Research. 2008 | Pubmed ID: 18421224 Alphavbeta5 Integrin Receptors at the Apical Surface of the RPE: One Receptor, Two Functions Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 18188966 Tetraspanin CD81 is Required for the Alpha V Beta5-integrin-dependent Particle-binding Step of RPE Phagocytosis Journal of Cell Science. Sep, 2007 | Pubmed ID: 17684062 Essential Role for MFG-E8 As Ligand for Alphavbeta5 Integrin in Diurnal Retinal Phagocytosis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17620600 The Lipofuscin Fluorophore A2E Perturbs Cholesterol Metabolism in Retinal Pigment Epithelial Cells Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007 | Pubmed ID: 17578916 MerTK Activation During RPE Phagocytosis in Vivo Requires AlphaVbeta5 Integrin Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249615 Altered Rhythm of Photoreceptor Outer Segment Phagocytosis in Beta5 Integrin Knockout Mice Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249564 Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium: a Potential Mechanism for Modulating Outer Segment Phagocytosis Under Oxidant Stress Conditions The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16354659 Novel Role for Alphavbeta5-integrin in Retinal Adhesion and Its Diurnal Peak American Journal of Physiology. Cell Physiology. Apr, 2006 | Pubmed ID: 16338970 Nonsynaptic Localization of the Excitatory Amino Acid Transporter 4 in Photoreceptors Molecular and Cellular Neurosciences. Mar, 2005 | Pubmed ID: 15737735 Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking Alphavbeta5 Integrin The Journal of Experimental Medicine. Dec, 2004 | Pubmed ID: 15596525 Changes in Retinal Pigment Epithelial Gene Expression Induced by Rod Outer Segment Uptake Investigative Ophthalmology & Visual Science. Jul, 2004 | Pubmed ID: 15223782 Comment on 'Integrin Alphavbbeta is Not Required for the Phagocytosis of Photoreceptor Outer Segments by Cultured Retinal Pigment Epithelial Cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286] Experimental Eye Research. Feb, 2004 | Pubmed ID: 14729363 Role of Alphavbeta5 Integrin in Regulating Phagocytosis by the Retinal Pigment Epithelium Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 15180282 Focal Adhesion Kinase Signaling Promotes Phagocytosis of Integrin-bound Photoreceptors The EMBO Journal. Aug, 2003 | Pubmed ID: 12912913 The Lipofuscin Component A2E Selectively Inhibits Phagolysosomal Degradation of Photoreceptor Phospholipid by the Retinal Pigment Epithelium Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904436 रेटिना वर्णक उपकला कोशिकाओं पर Phagocytosis Assays के लिए सुअर या गोजातीय फोटोरिसेप्टर बाहरी क्षेत्रों में बड़े पैमाने पर शुद्धीकरण Célia Parinot1,2,3, Quentin Rieu1,2,3, Jonathan Chatagnon1,2,3, Silvia C. Finnemann4, Emeline F. Nandrot1,2,3 1INSERM, U968, 2Sorbonne Universités, UPMC Paris 06, UMR_S 968, Institut de la Vision, 3CNRS, UMR_7210, 4Department of Biological Sciences, Center for Cancer, Genetic Diseases and Gene Regulation, Fordham University Immunology and Infection
रेटिना वर्णक उपकला कोशिकाओं पर Phagocytosis Assays के लिए सुअर या गोजातीय फोटोरिसेप्टर बाहरी क्षेत्रों में बड़े पैमाने पर शुद्धीकरण Célia Parinot1,2,3, Quentin Rieu1,2,3, Jonathan Chatagnon1,2,3, Silvia C. Finnemann4, Emeline F. Nandrot1,2,3 1INSERM, U968, 2Sorbonne Universités, UPMC Paris 06, UMR_S 968, Institut de la Vision, 3CNRS, UMR_7210, 4Department of Biological Sciences, Center for Cancer, Genetic Diseases and Gene Regulation, Fordham University Immunology and Infection