Simon M. Petersen-Jones College of Veterinary Medicine, Department of Small Animal Clinical Sciences Michigan State University Biography Publications Institution JoVE Articles Simon M. Petersen-Jones has not added a biography. If you are Simon M. Petersen-Jones and would like to personalize this page please email our Author Liaison for assistance. Publications CNGB1-related Rod-cone Dystrophy: A Mutation Review and Update Human Mutation. Jun, 2021 | Pubmed ID: 33847019 ERG Assessment of Altered Retinal Function in Canine Models of Retinitis Pigmentosa and Monitoring of Response to Translatable Gene Augmentation Therapy Documenta Ophthalmologica. Advances in Ophthalmology. Apr, 2021 | Pubmed ID: 33818677 Comparison of Developmental Dynamics in Human Fetal Retina and Human Pluripotent Stem Cell-Derived Retinal Tissue Stem Cells and Development. 04, 2021 | Pubmed ID: 33677999 Novel AAV Capsids for Intravitreal Gene Therapy of Photoreceptor Disorders EMBO Molecular Medicine. Apr, 2021 | Pubmed ID: 33616280 A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs Cells. Jan, 2021 | Pubmed ID: 33435495 Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. 04, 2021 | Pubmed ID: 33052761 A Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy Genes. 11, 2020 | Pubmed ID: 33261176 Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium Translational Vision Science & Technology. 06, 2020 | Pubmed ID: 32832209 A Novel Mutation in PDE6B in Spanish Water Dogs with Early-onset Progressive Retinal Atrophy Veterinary Ophthalmology. Sep, 2020 | Pubmed ID: 32639685 Changes in Retinal Layer Thickness with Maturation in the Dog: an in Vivo Spectral Domain - Optical Coherence Tomography Imaging Study BMC Veterinary Research. Jun, 2020 | Pubmed ID: 32605619 Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy American Journal of Human Genetics. 06, 2020 | Pubmed ID: 32386558 Large Animal Models of Inherited Retinal Degenerations: A Review Cells. 04, 2020 | Pubmed ID: 32260251 A Review of Electroretinography Waveforms and Models and Their Application in the Dog Veterinary Ophthalmology. May, 2020 | Pubmed ID: 32196872 Development of a Protocol for Maintaining Viability While Shipping Organoid-derived Retinal Tissue Journal of Tissue Engineering and Regenerative Medicine. 02, 2020 | Pubmed ID: 31908157 Sildenafil Administration in Dogs Heterozygous for A Functional Null Mutation in Pde6a: Suppressed Rod-Mediated ERG Responses and Apparent Retinal Outer Nuclear Layer Thinning Advances in Experimental Medicine and Biology. 2019 | Pubmed ID: 31884640 Advancing Gene Therapy for PDE6A Retinitis Pigmentosa Advances in Experimental Medicine and Biology. 2019 | Pubmed ID: 31884596 Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye Stem Cells and Development. 09, 2019 | Pubmed ID: 31210100 CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA Retina (Philadelphia, Pa.). Apr, 2019 | Pubmed ID: 30586351 Physiological Characterization of Ocular Melanosis-affected Canine Melanocytes Veterinary Ophthalmology. Mar, 2019 | Pubmed ID: 29701286 Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs Molecular Pharmacology. 05, 2018 | Pubmed ID: 29453250 Patients and Animal Models of CNGβ1-deficient Retinitis Pigmentosa Support Gene Augmentation Approach The Journal of Clinical Investigation. 01, 2018 | Pubmed ID: 29202463 Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human -Retinitis Pigmentosa Human Gene Therapy. Dec, 2017 | Pubmed ID: 29212382 Birth of Clones of the World's First Cloned Dog Scientific Reports. 11, 2017 | Pubmed ID: 29127382 Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs Investigative Ophthalmology & Visual Science. 06, 2017 | Pubmed ID: 28662231 Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response Investigative Ophthalmology & Visual Science. 01, 2017 | Pubmed ID: 28061512 A Tool Set to Allow Rapid Screening of Dog Families with PRA for Association with Candidate Genes Veterinary Ophthalmology. Jul, 2017 | Pubmed ID: 27317651 CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis Investigative Ophthalmology & Visual Science. Jul, 2016 | Pubmed ID: 27427859 An Association Between Systemic Cyclosporine Administration and Development of Acute Bullous Keratopathy in Cats Veterinary Ophthalmology. Jul, 2016 | Pubmed ID: 26880480 Progressive Retinal Atrophy in the Polski Owczarek Nizinny Dog: a Clinical and Genetic Study Veterinary Ophthalmology. May, 2016 | Pubmed ID: 26009980 Genetics of Canine Primary Glaucomas The Veterinary Clinics of North America. Small Animal Practice. Nov, 2015 | Pubmed ID: 26277300 Long-term Effect of Gene Therapy on Leber's Congenital Amaurosis The New England Journal of Medicine. May, 2015 | Pubmed ID: 25938638 Dog Models for Blinding Inherited Retinal Dystrophies Human Gene Therapy. Clinical Development. Mar, 2015 | Pubmed ID: 25671556 Isolation and Cultivation of Canine Uveal Melanocytes Veterinary Ophthalmology. Jul, 2015 | Pubmed ID: 25176505 Altered Fundus Appearance Resulting from Autofluorescence Imaging with the Confocal Scanning Laser Ophthalmoscope (cSLO) in Cats Veterinary Ophthalmology. Sep, 2014 | Pubmed ID: 24995729 A Partial Gene Deletion of SLC45A2 Causes Oculocutaneous Albinism in Doberman Pinscher Dogs PloS One. 2014 | Pubmed ID: 24647637 Successful Gene Therapy in Older Rpe65-deficient Dogs Following Subretinal Injection of an Adeno-associated Vector Expressing RPE65 Human Gene Therapy. Oct, 2013 | Pubmed ID: 24028205 A Large Animal Model for CNGB1 Autosomal Recessive Retinitis Pigmentosa PloS One. 2013 | Pubmed ID: 23977260 Evaluation of Lateral Spread of Transgene Expression Following Subretinal AAV-mediated Gene Delivery in Dogs PloS One. 2013 | Pubmed ID: 23560080 Exclusion of Eleven Candidate Genes for Ocular Melanosis in Cairn Terriers Journal of Negative Results in Biomedicine. Mar, 2013 | Pubmed ID: 23448350 A Facemask for Gaseous Anesthesia in Laboratory Rodents and Chicks That Allows Easy Access to the Eyes for Ophthalmic Procedures Veterinary Ophthalmology. Jul, 2013 | Pubmed ID: 23066660 Viral Vectors for Targeting the Canine Retina: a Review Veterinary Ophthalmology. Sep, 2012 | Pubmed ID: 22882429 Bilateral Uveal Metastasis of a Subcutaneous Fibrosarcoma in a Cat Veterinary Ophthalmology. Nov, 2012 | Pubmed ID: 22360781 Gene Augmentation Trials Using the Rpe65-deficient Dog: Contributions Towards Development and Refinement of Human Clinical Trials Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183331 Improvement of Visual Performance with Intravitreal Administration of 9-cis-retinal in Rpe65-mutant Dogs Archives of Ophthalmology (Chicago, Ill. : 1960). Nov, 2010 | Pubmed ID: 20837787 AAV Retinal Transduction in a Large Animal Model Species: Comparison of a Self-complementary AAV2/5 with a Single-stranded AAV2/5 Vector Molecular Vision. Sep, 2009 | Pubmed ID: 19756181 Characterization of a Canine Model of Autosomal Recessive Retinitis Pigmentosa Due to a PDE6A Mutation Investigative Ophthalmology & Visual Science. Feb, 2009 | Pubmed ID: 18775863 Topographical Characterization of Cone Photoreceptors and the Area Centralis of the Canine Retina Molecular Vision. 2008 | Pubmed ID: 19112529 A Novel Method for Objective Vision Testing in Canine Models of Inherited Retinal Disease Investigative Ophthalmology & Visual Science. Aug, 2008 | Pubmed ID: 18660425 Ocular Melanosis in the Cairn Terrier: Histopathological Description of the Condition, and Immunohistological and Ultrastructural Characterization of the Characteristic Pigment-laden Cells Veterinary Ophthalmology. Jul-Aug, 2008 | Pubmed ID: 18638353 Ocular Melanosis in the Cairn Terrier: Clinical Description and Investigation of Mode of Inheritance Veterinary Ophthalmology. Nov-Dec, 2007 | Pubmed ID: 17973836 Electroretinographic Features of the Retinopathy, Globe Enlarged (rge) Chick Phenotype Molecular Vision. Apr, 2007 | Pubmed ID: 17438521 Postnatal Development of Canine Axial Globe Length Measured by B-scan Ultrasonography Veterinary Ophthalmology. Jan-Feb, 2007 | Pubmed ID: 17204121 Influence of Recording Electrode Type and Reference Electrode Position on the Canine Electroretinogram Documenta Ophthalmologica. Advances in Ophthalmology. Sep, 2005 | Pubmed ID: 16514491 Assessment of the Dark-adaptation Time Required for Recovery of Electroretinographic Responses in Dogs After Fundus Photography and Indirect Ophthalmoscopy American Journal of Veterinary Research. Oct, 2005 | Pubmed ID: 16273914 Detailed Histopathologic Characterization of the Retinopathy, Globe Enlarged (rge) Chick Phenotype Molecular Vision. Jan, 2005 | Pubmed ID: 15660021 An Improved DNA-based Test for Detection of the Codon 616 Mutation in the Alpha Cyclic GMP Phosphodiesterase Gene That Causes Progressive Retinal Atrophy in the Cardigan Welsh Corgi Veterinary Ophthalmology. Jun, 2002 | Pubmed ID: 12071867 Sudden Acquired Retinal Degeneration Syndrome (SARDS) - a Review and Proposed Strategies Toward a Better Understanding of Pathogenesis, Early Diagnosis, and Therapy Veterinary Ophthalmology. | Pubmed ID: 26096588 Trapianto sottoretinico di tessuto retinico derivato da cellule staminali embrionali umane in un modello animale felino di grandi dimensioni Laurence M. Occelli*1, Felipe Marinho*1, Ratnesh K. Singh2, Francois Binette2, Igor O. Nasonkin2, Simon M. Petersen-Jones1 1College of Veterinary Medicine, Department of Small Animal Clinical Sciences, Michigan State University, 2Lineage Cell Therapeutics, Inc. JoVE 61683 Neuroscience
Trapianto sottoretinico di tessuto retinico derivato da cellule staminali embrionali umane in un modello animale felino di grandi dimensioni Laurence M. Occelli*1, Felipe Marinho*1, Ratnesh K. Singh2, Francois Binette2, Igor O. Nasonkin2, Simon M. Petersen-Jones1 1College of Veterinary Medicine, Department of Small Animal Clinical Sciences, Michigan State University, 2Lineage Cell Therapeutics, Inc. JoVE 61683 Neuroscience