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Articles by Tessa R. Davis in JoVE

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IP-FCM: Иммунопреципитация обнаружен с помощью проточной цитометрии


JoVE 2066 12/02/2010

Department of Immunology, College of Medicine, Mayo Clinic

IP-ТСМ метод представляется, что позволяет чувствительный, надежный, биохимическая оценка родной белок-белковых взаимодействий, не требуя генной инженерии или больших размеров образца.

Other articles by Tessa R. Davis on PubMed

Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

α1,3-Galactosyltransferase gene knockout (GTKO) pigs reduced the significance of antibody to galactose alpha 1,3-galactose (Gal) antigens but did not eliminate delayed xenograft rejection (DXR). We hypothesize that DXR of GTKO organs results from an antibody response to a limited number of non-Gal endothelial cell (EC) membrane antigens. In this study, we screened a retrovirus expression library to identify EC membrane antigens detected after cardiac xenotransplantation.

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