Tobias Pukrop

Department of Hematology and Oncology, university of göttingen

Affiliated withuniversity of göttingen University Medical Center Göttingen University Hospital Regensburg

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 32	2013
Publication title Cited by 98	2014
Publication title Cited by 1	2026

Other Publications

Article	Year
Mesengenic progenitor cells derived from human placenta. Tissue engineering\| PubMed ID: 15363170	2004
B-cell chronic lymphocytic leukemia with aberrant CD8 expression: genetic and immunophenotypic analysis of prognostic factors. Leukemia & lymphoma\| PubMed ID: 15370224	2004
Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16002723	2005
Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells. DNA and cell biology\| PubMed ID: 16274297	2005
The complex pathways of Wnt 5a in cancer progression. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 17952396	2008
Stromal endothelin B receptor-deficiency inhibits breast cancer growth and metastasis. Molecular cancer therapeutics\| PubMed ID: 19671740	2009
Effects of "minimally invasive curricular surgery" - a pilot intervention study to improve the quality of bedside teaching in medical education. Medical teacher\| PubMed ID: 19811179	2009
[A contribution to the needs assessment of faculty development measures in medical schools]. Medizinische Klinik (Munich, Germany : 1983)\| PubMed ID: 19916073	2009
Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII. Cancer research\| PubMed ID: 20233865	2010
Impact of teaching and assessment format on electrocardiogram interpretation skills. Medical education\| PubMed ID: 20528994	2010
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia\| PubMed ID: 20549749	2010
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. Carcinogenesis\| PubMed ID: 21983179	2011
German medical students lack knowledge of how to treat smoking and problem drinking. Addiction (Abingdon, England)\| PubMed ID: 22551065	2012
Student perceptions of evaluation in undergraduate medical education: A qualitative study from one medical school. BMC medical education\| PubMed ID: 22726271	2012
Piloting an outcome-based programme evaluation tool in undergraduate medical education. GMS Zeitschrift fÃ¼r medizinische Ausbildung\| PubMed ID: 22737199	2012
Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia\| PubMed ID: 22911652	2012
Estimating learning outcomes from pre- and posttest student self-assessments: a longitudinal study. Academic medicine : journal of the Association of American Medical Colleges\| PubMed ID: 23348083	2013
Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma. The American journal of pathology\| PubMed ID: 23375451	2013
Carcinoma cells misuse the host tissue damage response to invade the brain. Glia\| PubMed ID: 23832647	2013
Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Developmental biology\| PubMed ID: 23850867	2013
Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam3CSK 4 (BLP). Cancer immunology, immunotherapy : CII\| PubMed ID: 23917775	2013
Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion. Oncotarget\| PubMed ID: 24036536	2013
The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study. Oncotarget\| PubMed ID: 26299612	2015
Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data. PloS one\| PubMed ID: 26632845	2015
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clinical & experimental metastasis\| PubMed ID: 26862065	2016
Incipient Melanoma Brain Metastases Instigate Astrogliosis and Neuroinflammation. Cancer research\| PubMed ID: 27261506	2016
Inactivation of the LKB1-AMPK signaling pathway does not contribute to salivary gland tumor development - a short report. Cellular oncology (Dordrecht, Netherlands)\| PubMed ID: 27480082	2016
3D Coculture Model of the Brain Parenchyma-Metastasis Interface of Brain Metastasis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28634946	2017
Extent of Resection in Newly Diagnosed Glioblastoma: Impact of a Specialized Neuro-Oncology Care Center. Brain sciences\| PubMed ID: 29295569	2017
Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFR NSCLC in diagnosis, follow-up and treatment. Oncotarget\| PubMed ID: 29721166	2018
PI3K: A master regulator of brain metastasis-promoting macrophages/microglia. Glia\| PubMed ID: 30357946	2018
Peroxisome Proliferator-Activated Receptors (PPAR)γ Agonists as Master Modulators of Tumor Tissue. International journal of molecular sciences\| PubMed ID: 30424016	2018
Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis. Frontiers in pharmacology\| PubMed ID: 30546308	2018
A Blazing Landscape: Neuroinflammation Shapes Brain Metastasis. Cancer research\| PubMed ID: 30679177	2019
Cerebral metastases: do size, peritumoral edema, or multiplicity predict infiltration into brain parenchyma? Acta neurochirurgica\| PubMed ID: 30877471	2019
Inflammatory Activation of Astrocytes Facilitates Melanoma Brain Tropism via the CXCL10-CXCR3 Signaling Axis. Cell reports\| PubMed ID: 31412247	2019
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell reports\| PubMed ID: 31577944	2019
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. International journal of cancer\| PubMed ID: 31626715	2020
High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Molecular oncology\| PubMed ID: 31825135	2020
Anakoinosis: Correcting Aberrant Homeostasis of Cancer Tissue-Going Beyond Apoptosis Induction. Frontiers in oncology\| PubMed ID: 31921665	2019
5-Aminolevulinic Acid Fluorescence Indicates Perilesional Brain Infiltration in Brain Metastases. World neurosurgery: X\| PubMed ID: 32095783	2020
Melanoma brain metastases - Interdisciplinary management recommendations 2020. Cancer treatment reviews\| PubMed ID: 32736188	2020
A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology. Acta neuropathologica communications\| PubMed ID: 32758285	2020
Coronavirus disease 2019 induces multi-lineage, morphologic changes in peripheral blood cells. EJHaem\| PubMed ID: 32838398	2020
Single-institution cross-sectional study to evaluate need for information and need for referral to psychooncology care in association with depression in brain tumor patients and their family... BMC psychology\| PubMed ID: 32912313	2020
Secondary hemophagocytic lymphohistiocytosis and severe liver injury induced by hepatic SARS-CoV-2 infection unmasking Wilson's disease: Balancing immunosuppression. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases\| PubMed ID: 33412272	2021
Brain Metastases in Elderly Patients-The Role of Surgery in the Context of Systemic Treatment. Brain sciences\| PubMed ID: 33477588	2021
A Randomized Phase II Trial Comparing the Efficacy and Safety of Pioglitazone, Clarithromycin and Metronomic Low-Dose Chemotherapy with Single-Agent Nivolumab Therapy in Patients with Advanc... Frontiers in pharmacology\| PubMed ID: 33796020	2021
Identification and In-Depth Analysis of the Novel FGFR2-NDC80 Fusion in a Cholangiocarcinoma Patient: Implication for Therapy. Current oncology (Toronto, Ont.)\| PubMed ID: 33800328	2021
The Management of Brain Metastases-Systematic Review of Neurosurgical Aspects. Cancers\| PubMed ID: 33807384	2021
Modeling and Bioinformatics Identify Responders to G-CSF in Patients With Amyotrophic Lateral Sclerosis. Frontiers in neurology\| PubMed ID: 33815246	2021
Application of Lipid Class Ratios for Sample Stability Monitoring-Evaluation of Murine Tissue Homogenates and SDS as a Stabilizer. Metabolites\| PubMed ID: 33925735	2021
Sleep apnoea and incident malignancy in type 2 diabetes. ERJ open research\| PubMed ID: 34007843	2021
Self-reported fatigue in patients with rheumatoid arthritis compared to patients with cancer: results from two large-scale studies. Rheumatology international\| PubMed ID: 34272604	2022
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone. The Journal of clinical investigation\| PubMed ID: 34779418	2021
WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer. Journal of experimental & clinical cancer research : CR\| PubMed ID: 34911552	2021
Gemcitabine Maintenance Therapy in Patients With Metastasized Soft Tissue Sarcomas. Frontiers in oncology\| PubMed ID: 34970483	2021
Breakouts-A Radiological Sign of Poor Prognosis in Patients With Brain Metastases. Frontiers in oncology\| PubMed ID: 35444944	2022
Drug Repurposing by Tumor Tissue Editing. Frontiers in oncology\| PubMed ID: 35814409	2022
Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain. Oncogene\| PubMed ID: 36224342	2022
Identification of Disparities in Personalized Cancer Care-A Joint Approach of the German WERA Consortium. Cancers\| PubMed ID: 36291825	2022
Critical evaluation of molecular tumour board outcomes following 2 years of clinical practice in a Comprehensive Cancer Centre. British journal of cancer\| PubMed ID: 36572733	2023
Reciprocal interactions between innate immune cells and astrocytes facilitate neuroinflammation and brain metastasis via lipocalin-2. Nature cancer\| PubMed ID: 36797502	2023
Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States. Journal of Crohn's & colitis\| PubMed ID: 36961872	2023
Medical Needs and Therapeutic Options for Melanoma Patients Resistant to Anti-PD-1-Directed Immune Checkpoint Inhibition. Cancers\| PubMed ID: 37444558	2023
Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity? Cancers\| PubMed ID: 37760634	2023
Addressing Genetic Tumor Heterogeneity, Post-Therapy Metastatic Spread, Cancer Repopulation, and Development of Acquired Tumor Cell Resistance. Cancers\| PubMed ID: 38201607	2023
Peroxisome proliferator-activated receptorα/γ agonist pioglitazone for rescuing relapsed or refractory neoplasias by unlocking phenotypic plasticity. Frontiers in oncology\| PubMed ID: 38273846	2023
Organotypic 3D Ex Vivo Co-culture Model of the Macro-metastasis/Organ Parenchyma Interface. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 38393595	2024
The effects of Phoniatric PREhabilitation in Head and Neck Cancer patients on Aspiration and Preservation of Swallowing (PREHAPS): study protocol of a monocentric prospective randomized inte... Trials\| PubMed ID: 38519961	2024
A database for oncological research and quality assurance: implementation and first experiences with the University Clinical Cancer Registry Regensburg. BMC medical research methodology\| PubMed ID: 38539095	2024
The WERA cancer center matrix: Strategic management of patient access to precision oncology in a large and mostly rural area of Germany. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 38852290	2024
Attenuation of the BOLD fMRI Signal and Changes in Functional Connectivity Affecting the Whole Brain in Presence of Brain Metastasis. Cancers\| PubMed ID: 38893128	2024
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity. International journal of molecular sciences\| PubMed ID: 39125804	2024
Systematic development of a patient-reported ONCOlogical-ROUTinE-Screening (ONCO-ROUTES) procedure at the University Cancer Center Regensburg. Journal of cancer research and clinical oncology\| PubMed ID: 39340547	2024
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients. Molecular oncology\| PubMed ID: 39367702	2025
The Tumor Metabolite 5'-Deoxy-5'Methylthioadenosine (MTA) Inhibits Maturation and T Cell-Stimulating Capacity of Dendritic Cells. Cells\| PubMed ID: 39768204	2024
Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data. BMJ open\| PubMed ID: 39809556	2025
Preliminary effectiveness of social prescription and virtual patient information in increasing tertiary prevention among cancer patients (ESPRIT): protocol for a single-centre, randomised co... BMJ open\| PubMed ID: 39832968	2025
The spleen-liver axis supports obesity-induced systemic and fatty liver inflammation via MDSC and NKT cell enrichment. Molecular and cellular endocrinology\| PubMed ID: 40054835	2025
MEPED as salvage therapy for relapsed/refractory Hodgkin's lymphoma incorporating edited non-oncogene addiction: mTOR as a bottleneck. Frontiers in pharmacology\| PubMed ID: 40183103	2025
The EORTC QLQ-F17 as a shortened version of the EORTC QLQ-C30 to assess self-reported functioning in cancer patients: investigating equivalence and psychometric properties in a randomized cr... EClinicalMedicine\| PubMed ID: 40521164	2025
Primary and secondary metastatic dissemination: multiple routes to cancer-related death. Molecular cancer\| PubMed ID: 40696378	2025
MetInfilt: A prospective trial highlighting the importance of the histological growth pattern in brain metastases. Translational oncology\| PubMed ID: 40712433	2025
Development of a digitalization concept for assessing patient-reported outcomes in the context of a University Cancer Center - a model for use in clinical routine. Journal of patient-reported outcomes\| PubMed ID: 40924314	2025
Correction: Hassel et al. Medical Needs and Therapeutic Options for Melanoma Patients Resistant to Anti-PD-1-Directed Immune Checkpoint Inhibition. 2023, , 3448. Cancers\| PubMed ID: 41375089	2025
Supplementary biomarker testing in molecular tumor boards increases actionable therapy recommendations: a prospective real-world study of 658 patients. BMC medicine\| PubMed ID: 41530754	2026