Tomohiro Miyasaka

Publications

• Mass Spectrometry Imaging in Alzheimer's Disease
  Brain Connectivity. Aug, 2023  |   Pubmed ID: 36905365
• The Senile Plaque: Morphological Differences in APP Knock-in Mice Brains by Fixatives
  Brain and Behavior. Apr, 2023  |   Pubmed ID: 36879381
• Identification of Tau Protein As a Novel Marker for Maturation and Pathological Changes of Oligodendrocytes
  Glia. Apr, 2023  |   Pubmed ID: 36565228
• The Organization of Microtubules and Tau in Oligodendrocytes: Tau Pathology in Damaged Oligodendrocytes
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 36274848
• Quantum-dot-labeled Synuclein Seed Assay Identifies Drugs Modulating the Experimental Prion-like Transmission
  Communications Biology. Jun, 2022  |   Pubmed ID: 35768587
• Microtubule Assembly by Tau Impairs Endocytosis and Neurotransmission Via Dynamin Sequestration in Alzheimer's Disease Synapse Model
  ELife. Apr, 2022  |   Pubmed ID: 35471147
• Therapeutic Effect of a Novel Curcumin Derivative GT863 on a Mouse Model of Amyotrophic Lateral Sclerosis
  Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. Nov, 2022  |   Pubmed ID: 34894926
• Disulfide Bond Formation in Microtubule-associated Tau Protein Promotes Tau Accumulation and Toxicity in Vivo
  Human Molecular Genetics. Oct, 2021  |   Pubmed ID: 34137825
• Quantitative Fractionation of Tissue Microtubules with Distinct Biochemical Properties Reflecting Their Stability and Lability
  Biochemical and Biophysical Research Communications. Jun, 2021  |   Pubmed ID: 33992960
• A Potential Defense Mechanism Against Amyloid Deposition in Cerebellum
  Biochemical and Biophysical Research Communications. Jan, 2021  |   Pubmed ID: 33340762
• The Inducible Amphisome Isolates Viral Hemagglutinin and Defends Against Influenza A Virus Infection
  Nature Communications. Jan, 2020  |   Pubmed ID: 31919357
• Inhibition of Microtubule Assembly Competent Tubulin Synthesis Leads to Accumulation of Phosphorylated Tau in Neuronal Cell Bodies
  Biochemical and Biophysical Research Communications. Jan, 2020  |   Pubmed ID: 31699369
• Regulatory Mechanisms for the Axonal Localization of Tau Protein in Neurons
  Molecular Biology of the Cell. Sep, 2019  |   Pubmed ID: 31364926
• Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2019  |   Pubmed ID: 31235644
• Distribution of Endogenous Normal Tau in the Mouse Brain
  The Journal of Comparative Neurology. Apr, 2019  |   Pubmed ID: 30408165
• Distribution of Oxidized DJ-1 in Parkinson's Disease-related Sites in the Brain and in the Peripheral Tissues: Effects of Aging and a Neurotoxin
  Scientific Reports. Aug, 2018  |   Pubmed ID: 30104666
• Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in Models of Tauopathy
  Frontiers in Neuroscience. 2018  |   Pubmed ID: 29973863
• Isoform-independent and -dependent Phosphorylation of Microtubule-associated Protein Tau in Mouse Brain During Postnatal Development
  The Journal of Biological Chemistry. 02, 2018  |   Pubmed ID: 29196605
• Distinct Deposition of Amyloid-β Species in Brains with Alzheimer's Disease Pathology Visualized with MALDI Imaging Mass Spectrometry
  Acta Neuropathologica Communications. 10, 2017  |   Pubmed ID: 29037261
• The Role of the Carboxyl-Terminal Sequence of Tau and MAP2 in the Pathogenesis of Dementia
  Frontiers in Molecular Neuroscience. 2016  |   Pubmed ID: 28082867
• Curcumin Improves Tau-induced Neuronal Dysfunction of Nematodes
  Neurobiology of Aging. Mar, 2016  |   Pubmed ID: 26923403
• Toxic Tau Oligomer Formation Blocked by Capping of Cysteine Residues with 1,2-dihydroxybenzene Groups
  Nature Communications. Dec, 2015  |   Pubmed ID: 26671725
• Identification of Key Amino Acids Responsible for the Distinct Aggregation Properties of Microtubule-associated Protein 2 and Tau
  Journal of Neurochemistry. Oct, 2015  |   Pubmed ID: 26134402
• Immunostaining of Oxidized DJ-1 in Human and Mouse Brains
  Journal of Neuropathology and Experimental Neurology. Jul, 2014  |   Pubmed ID: 24918637
• The Homologous Carboxyl-terminal Domains of Microtubule-associated Protein 2 and TAU Induce Neuronal Dysfunction and Have Differential Fates in the Evolution of Neurofibrillary Tangles
  PloS One. 2014  |   Pubmed ID: 24587039
• Substrate Ectodomain is Critical for Substrate Preference and Inhibition of γ-secretase
  Nature Communications. 2013  |   Pubmed ID: 24108142
• Central Nervous System-specific Deletion of Transcription Factor Nrf1 Causes Progressive Motor Neuronal Dysfunction
  Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jun, 2011  |   Pubmed ID: 21554501
• Microtubule Destruction Induces Tau Liberation and Its Subsequent Phosphorylation
  FEBS Letters. Jul, 2010  |   Pubmed ID: 20561519
• Anesthesia-induced Hyperphosphorylation Detaches 3-repeat Tau from Microtubules Without Affecting Their Stability in Vivo
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008  |   Pubmed ID: 19036972
• Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived IPSCs
  Stem Cell Reports.   |   Pubmed ID: 31543469