William P. Schiemann Case Comprehensive Cancer Center Case Western Reserve University Biography Publications Institution JoVE Articles William P. Schiemann has not added a biography. If you are William P. Schiemann and would like to personalize this page please email our Author Liaison for assistance. Publications Deconstructing the Mechanisms and Consequences of TGF-β-induced EMT During Cancer Progression Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21691718 Role of TGF-β and the Tumor Microenvironment During Mammary Tumorigenesis Gene Expression. 2011 | Pubmed ID: 22268294 NetSlim: High-confidence Curated Signaling Maps Database : the Journal of Biological Databases and Curation. 2011 | Pubmed ID: 21959865 β3 Integrin-EGF Receptor Cross-talk Activates P190RhoGAP in Mouse Mammary Gland Epithelial Cells Molecular Biology of the Cell. Nov, 2011 | Pubmed ID: 21937717 Krüppel-like Factor 4 Inhibits Tumorigenic Progression and Metastasis in a Mouse Model of Breast Cancer Neoplasia (New York, N.Y.). Jul, 2011 | Pubmed ID: 21750654 Down-regulation of Epithelial Cadherin is Required to Initiate Metastatic Outgrowth of Breast Cancer Molecular Biology of the Cell. Jul, 2011 | Pubmed ID: 21613543 Lysyl Oxidase Contributes to Mechanotransduction-mediated Regulation of Transforming Growth Factor-β Signaling in Breast Cancer Cells Neoplasia (New York, N.Y.). May, 2011 | Pubmed ID: 21532881 Noncanonical TGF-β Signaling During Mammary Tumorigenesis Journal of Mammary Gland Biology and Neoplasia. Jun, 2011 | Pubmed ID: 21448580 Fibromodulin Suppresses Nuclear Factor-kappaB Activity by Inducing the Delayed Degradation of IKBA Via a JNK-dependent Pathway Coupled to Fibroblast Apoptosis The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21156791 The Cain and Abl of Epithelial-mesenchymal Transition and Transforming Growth Factor-β in Mammary Epithelial Cells Cells, Tissues, Organs. 2011 | Pubmed ID: 21051857 Transforming Growth Factor-β and the Hallmarks of Cancer Cellular Signalling. Jun, 2011 | Pubmed ID: 20940046 Colorectal Cancer in the Cotton Top Tamarin (Saguinus Oedipus): How Do They Evade Liver Metastasis? Digestive Diseases and Sciences. Feb, 2011 | Pubmed ID: 20645001 Homeoprotein Six1 Increases TGF-beta Type I Receptor and Converts TGF-beta Signaling from Suppressive to Supportive for Tumor Growth Cancer Research. Dec, 2010 | Pubmed ID: 21056993 The Pathophysiology of Epithelial-mesenchymal Transition Induced by Transforming Growth Factor-beta in Normal and Malignant Mammary Epithelial Cells Journal of Mammary Gland Biology and Neoplasia. Jun, 2010 | Pubmed ID: 20467795 Repo-man Controls a Protein Phosphatase 1-dependent Threshold for DNA Damage Checkpoint Activation Current Biology : CB. Mar, 2010 | Pubmed ID: 20188555 PGE2 Receptor EP2 Mediates the Antagonistic Effect of COX-2 on TGF-beta Signaling During Mammary Tumorigenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2010 | Pubmed ID: 19897661 Mechanisms of the Epithelial-mesenchymal Transition by TGF-beta Future Oncology (London, England). Oct, 2009 | Pubmed ID: 19852727 Epithelial-mesenchymal Transition in Tumor Metastasis: a Method to the Madness Future Oncology (London, England). Oct, 2009 | Pubmed ID: 19852724 P130Cas is Required for Mammary Tumor Growth and Transforming Growth Factor-beta-mediated Metastasis Through Regulation of Smad2/3 Activity The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19822523 Therapeutic Targeting of the Focal Adhesion Complex Prevents Oncogenic TGF-beta Signaling and Metastasis Breast Cancer Research : BCR. 2009 | Pubmed ID: 19740433 The Six1 Homeoprotein Induces Human Mammary Carcinoma Cells to Undergo Epithelial-mesenchymal Transition and Metastasis in Mice Through Increasing TGF-beta Signaling The Journal of Clinical Investigation. Sep, 2009 | Pubmed ID: 19726885 Preclinical Efficacy of Cystatin C to Target the Oncogenic Activity of Transforming Growth Factor Beta in Breast Cancer Translational Oncology. Aug, 2009 | Pubmed ID: 19701502 Activated Abl Kinase Inhibits Oncogenic Transforming Growth Factor-beta Signaling and Tumorigenesis in Mammary Tumors FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2009 | Pubmed ID: 19690215 X-linked Inhibitor of Apoptosis Protein and Its E3 Ligase Activity Promote Transforming Growth Factor-{beta}-mediated Nuclear Factor-{kappa}B Activation During Breast Cancer Progression The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19531477 The TGF-beta Paradox in Human Cancer: an Update Future Oncology (London, England). Mar, 2009 | Pubmed ID: 19284383 Cox-2 Inactivates Smad Signaling and Enhances EMT Stimulated by TGF-beta Through a PGE2-dependent Mechanisms Carcinogenesis. Nov, 2008 | Pubmed ID: 18725385 Transcriptional and Translational Regulation of TGF-beta Production in Response to Apoptotic Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18714031 Fibulin-5 Initiates Epithelial-mesenchymal Transition (EMT) and Enhances EMT Induced by TGF-beta in Mammary Epithelial Cells Via a MMP-dependent Mechanism Carcinogenesis. Dec, 2008 | Pubmed ID: 18713838 Microfibril-associate Glycoprotein-2 (MAGP-2) Promotes Angiogenic Cell Sprouting by Blocking Notch Signaling in Endothelial Cells Microvascular Research. May, 2008 | Pubmed ID: 18417156 Altered TAB1:I KappaB Kinase Interaction Promotes Transforming Growth Factor Beta-mediated Nuclear Factor-kappaB Activation During Breast Cancer Progression Cancer Research. Mar, 2008 | Pubmed ID: 18316610 Grb2 Binding to Tyr284 in TbetaR-II is Essential for Mammary Tumor Growth and Metastasis Stimulated by TGF-beta Carcinogenesis. Feb, 2008 | Pubmed ID: 18174260 Transcriptome Analysis of Endothelial Cell Gene Expression Induced by Growth on Matrigel Matrices: Identification and Characterization of MAGP-2 and Lumican As Novel Regulators of Angiogenesis Angiogenesis. 2007 | Pubmed ID: 17632767 Targeted TGF-beta Chemotherapies: Friend or Foe in Treating Human Malignancies? Expert Review of Anticancer Therapy. May, 2007 | Pubmed ID: 17492924 Src Phosphorylates Tyr284 in TGF-beta Type II Receptor and Regulates TGF-beta Stimulation of P38 MAPK During Breast Cancer Cell Proliferation and Invasion Cancer Research. Apr, 2007 | Pubmed ID: 17440088 Role of Transforming Growth Factor-beta in Cancer Progression Future Oncology (London, England). Dec, 2006 | Pubmed ID: 17155901 Apoptotic Cells, Through Transforming Growth Factor-beta, Coordinately Induce Anti-inflammatory and Suppress Pro-inflammatory Eicosanoid and NO Synthesis in Murine Macrophages The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17056601 Beta3 Integrin and Src Facilitate Transforming Growth Factor-beta Mediated Induction of Epithelial-mesenchymal Transition in Mammary Epithelial Cells Breast Cancer Research : BCR. 2006 | Pubmed ID: 16859511 TGF-beta in Cancer and Other Diseases Future Oncology (London, England). Apr, 2006 | Pubmed ID: 16563087 Fibulins 3 and 5 Antagonize Tumor Angiogenesis in Vivo Cancer Research. Mar, 2006 | Pubmed ID: 16510581 Fibulin-5 Function During Tumorigenesis Future Oncology (London, England). Feb, 2005 | Pubmed ID: 16555973 The Use of Cystatin C to Inhibit Epithelial-mesenchymal Transition and Morphological Transformation Stimulated by Transforming Growth Factor-beta Breast Cancer Research : BCR. 2005 | Pubmed ID: 16168131 Identification and Characterization of Regulator of G Protein Signaling 4 (RGS4) As a Novel Inhibitor of Tubulogenesis: RGS4 Inhibits Mitogen-activated Protein Kinases and Vascular Endothelial Growth Factor Signaling Molecular Biology of the Cell. Feb, 2005 | Pubmed ID: 15548600 Fibulin-2 and Fibulin-5 Alterations in Tsk Mice Associated with Disorganized Hypodermal Elastic Fibers and Skin Tethering The Journal of Investigative Dermatology. Dec, 2004 | Pubmed ID: 15610515 Fibulin-5 Promotes Wound Healing in Vivo Journal of the American College of Surgeons. Sep, 2004 | Pubmed ID: 15325610 Fibulin-5 Antagonizes Vascular Endothelial Growth Factor (VEGF) Signaling and Angiogenic Sprouting by Endothelial Cells DNA and Cell Biology. Jun, 2004 | Pubmed ID: 15231070 Pigment Epithelium-derived Factor in Idiopathic Pulmonary Fibrosis: a Role in Aberrant Angiogenesis American Journal of Respiratory and Critical Care Medicine. Aug, 2004 | Pubmed ID: 15117744 Transforming Growth Factor-beta (TGF-beta)-resistant B Cells from Chronic Lymphocytic Leukemia Patients Contain Recurrent Mutations in the Signal Sequence of the Type I TGF-beta Receptor Cancer Detection and Prevention. 2004 | Pubmed ID: 15041079 Cystatin C Antagonizes Transforming Growth Factor Beta Signaling in Normal and Cancer Cells Molecular Cancer Research : MCR. Mar, 2004 | Pubmed ID: 15037657 Cloning of a Novel Signaling Molecule, AMSH-2, That Potentiates Transforming Growth Factor Beta Signaling BMC Cell Biology. Jan, 2004 | Pubmed ID: 14728725 Development of Human Protein Reference Database As an Initial Platform for Approaching Systems Biology in Humans Genome Research. Oct, 2003 | Pubmed ID: 14525934 SPARC Inhibits Epithelial Cell Proliferation in Part Through Stimulation of the Transforming Growth Factor-beta-signaling System Molecular Biology of the Cell. Oct, 2003 | Pubmed ID: 14517312 Context-specific Effects of Fibulin-5 (DANCE/EVEC) on Cell Proliferation, Motility, and Invasion. Fibulin-5 is Induced by Transforming Growth Factor-beta and Affects Protein Kinase Cascades The Journal of Biological Chemistry. Jul, 2002 | Pubmed ID: 12021267 Cross-talk Between ERK and P38 MAPK Mediates Selective Suppression of Pro-inflammatory Cytokines by Transforming Growth Factor-beta The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11842088 В естественных условиях двойного основания Bioluminescent изображений Michael K. Wendt1, Joseph Molter1, Christopher A. Flask1, William P. Schiemann1 1Case Comprehensive Cancer Center, Case Western Reserve University JoVE 3245 Medicine
В естественных условиях двойного основания Bioluminescent изображений Michael K. Wendt1, Joseph Molter1, Christopher A. Flask1, William P. Schiemann1 1Case Comprehensive Cancer Center, Case Western Reserve University JoVE 3245 Medicine