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Isolation and Characterization of Bone Marrow Microenvironment in Myeloid Neoplasms

November 10th, 2023
1,2, 1,3, 1,3, 1,2, 1,3,4, 1,5, 1,3
1Wilmot Cancer Institute, University of Rochester Medical Center, 2Department of Biomedical Engineering, University of Rochester, 3Department of Biomedical Genetics, University of Rochester Medical Center, 4Genomics Research Center, University of Rochester Medical Center, 5Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center

Summary
Automatic Translation

Her presenteres en detaljert protokoll for å isolere og karakterisere benmargens mikromiljøpopulasjoner fra murine modeller av myelodysplastiske syndromer og akutt myelogen leukemi. Denne teknikken identifiserer endringer i den ikke-hematopoietiske benmargnisjen, inkludert endotel- og mesenkymale stromale celler, med sykdomsprogresjon.

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