Tibet Rhodiola Pharmaceutical Holding Co. Ltd 1 article published in JoVE Medicine An In Vitro Dissolution Determination of Multi-Index Components in Tibetan Medicine Rhodiola Granules Qinyun Du1, Qingxiu He2, Fengming Zhang3, Jiao Mi3, Yuying Li3, Shaohui Wang1, Yi Zhang1 1School of Pharmacy, Chengdu University of Traditional Chinese Medicine, 2School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, 3Tibet Rhodiola Pharmaceutical Holding Co. Ltd Here, we test the dissolution of Rhodiola granules (RG) in vitro, draw dissolution curves of salidroside, gallic acid, and ethyl gallate in ultrapure water, and fit the curves to different mathematical models. This protocol provides information and guidance for in vivo bioequivalence and in vivo-in vitro correlation studies of RG.
