West China Hospital of Stomatology 1 article published in JoVE Medicine Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy Yiming Song*1, Peiran Li*2, Ping Lyu1, Yanshen Yu1, Xinyu Chen1, Chen Cui3, Ruiye Bi2, Yi Fan1 1State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, 2State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, 3Guangdong Province Key Laboratory of Stomatology, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University An animal model of acquired hypoparathyroidism (HypoPT) is crucial to understanding how HypoPT affects mineral ion homeostasis and to verify the effectiveness of novel treatments. Here, a technique is presented to generate an acquired hypoparathyroidism (AHypoPT) rat model by parathyroidectomy (PTX) using carbon nanoparticles.
