Kangwon National University 4 articles published in JoVE Engineering Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom Jihun Kang1, Hojin Ha1 1Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University The present protocol describes particle image velocimetry (PIV) measurements performed to investigate the sinus flow through the in vitro setup of the transcatheter aortic valve (TAV). The hemodynamic parameters based on velocity are also determined. Engineering In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging Doohyeon Kim1, Hyung Kyu Huh2, Hojin Ha1 1Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University, 2Medical Device Development Center, DGMIF Aortic regurgitation is an aortic valve heart disease. This manuscript demonstrates how four-dimensional flow magnetic resonance imaging can evaluate aortic regurgitation using in vitro heart valves mimicking aortic regurgitation. Environment Cortisol Extraction from Sturgeon Fin and Jawbone Matrices Jalil Ghassemi Nejad1,2, Mohammad Ataallahi1, Mohammad H. Salmanzadeh3, Kyung T. Park3, Hong G. Lee2,4, Alireza Shoae5, Atieh Rahimi6, Kyung I. Sung1, Kyu H. Park1 1College of Animal Life Sciences, Kangwon National University, 2Team of An Educational Program for Specialists in Global Animal Science, Brain Korea 21 Plus Project, Konkuk University, 3Persian Gesture, 4Department of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, 5Department of Animal Science, Animal Physiology, AgResearch, 6Faculty of Agriculture, Animal Science Department, Ferdowsi University of Mashhad In this study, we present a protocol for cortisol extraction from the fin and jawbone of sturgeon species. Fin and jawbone cortisol levels were further examined by comparing two washing solvents followed by ELISA assays. This study piloted the feasibility of jawbone cortisol as a novel stress indicator. Cancer Research Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles Ji-Eun Chang1, Hyun-Jong Cho2, Sanghoon Jheon1,3 1Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, 2College of Pharmacy, Kangwon National University, 3Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine Photodynamic therapy (PDT) is an alternative choice for lung cancer treatment. To increase the therapeutic effect of PDT, lung cancer-targeted nanoparticles combined with chemotherapy were developed. Both in vitro and in vivo anticancer efficacies of PDT with prepared nanoparticles were evaluated.