Eaton Industries (Austria) GmbH 1 article published in JoVE Medicine Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System Patrick M. Pilz1, Miriam Lang1, Ouafa Hamza1, Petra L. Szabo1, Milat Inci1, Anne M. Kramer1, Michael Koch2, Johann Huber3, Bruno K. Podesser1, Attila Kiss1 1Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, 2Concept & Ideation, Electrical Sector/EMEA/Power Distribution Division, Eaton Industries (Austria) GmbH, 3Vetfarm and Clinical Unit for Herd Health Management in Ruminants, Clinic for Ruminants, Vetmeduni Vienna This article presents an efficient method to perform myocardial ischemia and subsequent chronic reperfusion in rats using a minimally invasive approach. In addition, left ventricular hemodynamic function of rats is assessed by echocardiography and isolated working heart methods.
