Charite University Medicine Berlin 2 articles published in JoVE Medicine Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model Yimeng Hao1,2, Xiaolin Sun1,2, Jonathan Frederik Sebastian Kiekenap1, Jasper Emeis1, Marvin Steitz2, Alexander Breitenstein-Attach2, Felix Berger1,2, Boris Schmitt1,2,3,4,5 1Department of Pediatric Cardiology and Congenital Heart Disease, Charité University Medicine Berlin, 2Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum Berlin, 3DZHK (German Centre for Cardiovascular Research) and BMBF (German Ministry of Education and Research), 4BIH (Berlin Institute of Health), 5BCRT (BIH Center of Regenerative Therapies) This study demonstrates the feasibility and safety of developing an autologous pulmonary valve for implantation at the native pulmonary valve position by using a self-expandable Nitinol stent in an adult sheep model. This is a step toward developing transcatheter pulmonary valve replacement for patients with right ventricular outflow tract dysfunction. Medicine Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement Xiaolin Sun*1,2, Yimeng Hao*1,2, Jonathan Frederik Sebastian Kiekenap1, Jasper Emeis1, Marvin Steitz2, Alexander Breitenstein-Attach2, Felix Berger1,2, Boris Schmitt1,2,3 1Department of Pediatric Cardiology and Congenital Heart Disease, Charité University Medicine Berlin, 2Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum Berlin, 3DZHK (German Centre for Cardiovascular Research) and BMBF (German Ministry of Education and Research) This study assessed a new methodology with a straightened model generated from the four-dimensional cardiac computed tomography sequence to obtain the desired measurements for valve sizing in the application of transcatheter pulmonary valve replacement.
