DZNE and University of Bonn

1 article published in JoVE

• Biology

  
  Cost-Efficient Transcriptomic-Based Drug Screening Jacqueline Leidner^1,2, Heidi Theis³, Michael Kraut³, Alice Ragogna¹, Marc Beyer^1,3,4, Joachim Schultze^1,2,3, Jonas Schulte-Schrepping^1,2, Caterina Carraro^1,2, Lorenzo Bonaguro^{1,2 1}Systems Medicine, German Center for Neurodegenerative Diseases (DZNE) eV., ²Genomics & Immunoregulation, LIMES Institute, University of Bonn, ³PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn, ⁴Immunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE) eV. This protocol describes a workflow from ex vivo or in vitro cell cultures to transcriptomic data pre-processing for cost-effective transcriptome-based drug screening.