Universidade da Coruna (UDC) 4 articles published in JoVE Engineering Evaluation of the Curing of Adhesive Systems by Rheological and Thermal Testing Ana Díaz-Díaz*1, Barbara Sánchez-Silva*1, Javier Tarrío-Saavedra*1, Jorge López-Beceiro*1, Silvia Gómez-Barreiro*1, Ramon Artiaga*1 1Escola Politécnica Superior, Universidade da Coruña An experimental methodology based on thermal and rheological measurements is proposed to characterize the curing process of adhesives with to obtain useful information for industrial adhesive selection. Chemistry Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection Diana Martínez-Matamoros1, Socorro Castro-García1, Gabriela Ojeda Romano2, Miguel Balado3, Jaime Rodríguez1, Manuel L. Lemos3, Carlos Jiménez1 1Centro de Investigacións Científicas Avanzadas (CICA), Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 2Centro de Investigacións Científicas Avanzadas (CICA), Unidad de Comunicación y Divulgación, Universidade da Coruña, 3Department of Microbiology and Parasitology, Institute of Aquaculture, Universidade de Santiago de Compostela This work describes protocols for the preparation of magnetic nanoparticles, its coating with SiO2, followed by its amine functionalization with (3-aminopropyl)triethoxysilane (APTES) and its conjugation with deferoxamine using a succinyl moiety as a linker. A deep structural characterization description and a capture bacteria assay using Y. enterocolitica for all the intermediate nanoparticles and the final conjugate are also described in detail. Medicine Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis Lucía Ramos1,2, Jorge Novo1,2, Noelia Barreira1,2, José Rouco1,2, Manuel G. Penedo1,2, Marcos Ortega1,2 1Department of Computer Science, University of A Coruña, 2CITIC-Research Center for Information and Communication Technologies, University of A Coruña This article presents a protocol based on Hydra — a web-based system for clinical decision support that integrates a full and detailed set of functionalities and services required by physicians for complete cardiovascular analysis, risk assessment, early diagnosis, treatment, and monitoring over time. Bioengineering Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation Ignasi Casanellas1,2, Anna Lagunas3,1, Iro Tsintzou1, Yolanda Vida4,5, Daniel Collado4,5, Ezequiel Pérez-Inestrosa4,5, Cristina Rodríguez-Pereira6, Joana Magalhaes3,6, Pau Gorostiza1,3,7, José A. Andrades8,3, José Becerra8,3,5, Josep Samitier1,3,2 1Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), 2Department of Engineering Electronics, University of Barcelona (UB), 3Networking Biomedical Research Center (CIBER), 4Instituto de Investigacin Biomédica de Málaga (IBIMA), Department of Organic Chemistry, Universidad de Málaga (UMA), 5Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, 6Unidad de Bioingeniería Tisular y Terapia Celular (GBTTC-CHUAC), Grupo de Reumatolog ía, Instituto de Investigación Biomèdica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 7Institució Catalana de Recerca i Estudis Avançats (ICREA), 8Instituto de Investigación Biomédica de Málaga (IBIMA), Department of Cell Biology, Genetics and Physiology, Universidad de Málaga (UMA) A method to obtain dendrimer-based uneven nanopatterns that permit the nanoscale control of local arginine-glycine-aspartic acid (RGD) surface density is described and applied for the study of cell adhesion and chondrogenic differentiation.
