Hospital Universitari de la Ribera 1 article published in JoVE Bioengineering Low-Dose Gamma Radiation Sterilization for Decellularized Tracheal Grafts Néstor J. Martínez-Hernández1, Lara Milián-Medina2, Jorge Mas-Estellés3, José L. Monroy-Antón4, José L. López-Villalobos5, David Hervás-Marín6, Amparo Roig-Bataller1, Manuel Mata-Roig2,7,8 1Thoracic Surgery Department, Hospital Universitari de la Ribera, 2Pathology Department, Universitat de Valencia Facultat de Medicina i Odontologia, 3Center for Biomaterials and Tissue Engineering, Universitat Politècnica de València, 4Radiation Oncology, Hospital Universitari de la Ribera, 5Thoracic Surgery Department, Hospitales Universitarios Virgen del Rocío, 6Department of Applied Statistics and Operations Research and Quality, Universitat Politècnica de València, 7Networking Research Center on Respiratory Diseases (CIBERER), 8INCLIVA Biomedical Research Institute Obtaining sterilization is essential for tracheal tissue transplant. Herein, we present a sterilization protocol using low-dose gamma irradiation that is fully tolerated by organs.
