University of Paris 1 article published in JoVE Medicine Assessing Intracardiac Vortices with High Frame-Rate Echocardiography-Derived Blood Speckle Imaging in Newborns Edward Crendal1, Koert De Waal2, Damien Vitiello3 1John Hunter Hospital, Department of Cardiology, University of Newcastle, 2John Hunter Children’s Hospital, Department of Neonatology, University of Newcastle, 3Institute of Sport and Health Sciences of Paris (IS3P - URP 3625), Université Paris Cité The present protocol uses echocardiography-derived blood speckle imaging technology to visualize intracardiac hemodynamics in newborns. The clinical utility of this technology is explored, the rotational body of fluid within the left ventricle (known as a vortex) is accessed, and its significance in understanding diastology is determined.