UCLH Biomedical Research Centre - NIHR 2 articles published in JoVE Engineering Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver Wenfeng Xia1,2, Simeon J. West3, Malcolm C. Finlay2,4, Rosalind Pratt5,6, Sunish Mathews1,2, Jean-Martial Mari7, Sebastien Ourselin1,2,6, Anna L. David1,5,8,9, Adrien E. Desjardins1,2 1Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, 2Department of Medical Physics and Biomedical Engineering, University College London, 3Department of Anaesthesia, University College Hospital, 4St Bartholomew's Hospital and Queen Mary University of London, 5Institute for Women's Health, University College London, 6Centre for Medical Imaging Computing, University College London, 7GePaSud, University of French Polynesia, 8Department of Development and Regeneration, KU Leuven (Katholieke Universiteit), 9NIHR University College London Hospitals Biomedical Research Centre Accurate and efficient visualization of invasive medical devices is extremely important in many ultrasound-guided minimally invasive procedures. Here, a method for localizing the spatial position of a needle tip relative to the ultrasound imaging probe is presented. Medicine Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield Andrea M. Collins1,2, Jamie Rylance3, Daniel G. Wootton4, Angela D. Wright3,5, Adam K. A. Wright1,3, Duncan G. Fullerton3,6, Stephen B. Gordon3 1Biomedical Research Centre in Microbial Diseases, National Institute for Health Research, 2Respiratory Infection Group, Royal Liverpool and Broadgreen University Hospital Trust, 3Respiratory Infection Group, Liverpool School of Tropical Medicine, 4Institute of Infection and Global Health, University of Liverpool, 5Comprehensive Local Research Network, Royal Liverpool and Broadgreen University Hospital Trust, 6Department of Respiratory Research, University Hospital Aintree We describe a research technique for fiberoptic bronchoscopy and bronchoalveolar lavage using low pressure suction. The technique is used to harvest immune cells from the lung bronchoalveolar surfaces. Local anesthetic and mild conscious sedation (midazolam) is used. Subjects tolerate the procedure well and experience minimal side effects.
