Foundation for Research and Technology 1 article published in JoVE Developmental Biology Detection of DNA Double-Stranded Breaks in Mouse Oocytes Chrysoula Zorzompokou1,2, Marios Ipeirotis1,2, Marios Kaisar Martzoukos1, Petros Marangos1,2 1Department of Biological Applications and Technology, University of Ioannina, 2Biomedical Research Institute, Foundation for Research and Technology Maintaining oocyte genome integrity is necessary to ensure the genetic fidelity in the resulting embryo. Here, we present an accurate protocol for detecting DNA double-strand breaks in mammalian female germ cells.
