- École Polytechnique Fédérale de Lausanne5 published articles
- Örebro University Hospital1 published article
- Bühlmann Laboratories1 published article
- Balgrist University Hospital1 published article
- ETH Zürich1 published article
- Friedrich Miescher Institute for Biomedical Research1 published article
- Institute for Research in Biomedicine1 published article
- Kantonsspital Aarau1 published article
- Swiss Institute of Bioinformatics (SIB)2 published articles
- Swiss Tropical and Public Health Institute1 published article
- Universität Basel4 published articles
- University Hospital of Geneva3 published articles
- University Hospital Zurich2 published articles
- University of Berne3 published articles
- University of Fribourg4 published articles
- University of Geneva5 published articles
- University of Lausanne3 published articles
- University of Zurich6 published articles
4 articles published in JoVE
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
1Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, 2University of Basel, Basel, Switzerland
Chronic infection with soil-transmitted helminths (STHs) causes malabsorption, stunting, and wasting in the growing child. Hence, it is plausible that these infections also reduce the physical fitness of children. Here, we visualize two techniques for the diagnosis of STHs and the 20-meter shuttle run test for assessing children's physical fitness.
A Functional Motor Unit in the Culture Dish: Co-culture of Spinal Cord Explants and Muscle Cells
Biozentrum, University of Basel
Cultured muscle cells are an inadequate model to recapitulate innervated muscle in vivo. A functional motor unit can be reproduced in vitro by innervation of differentiated human primary muscle cells using rat embryo spinal cord explants. This article describes how co-cultures of spinal cord explants and muscle cells are established.
The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures
Anatomical Institute, Department of Biomedicine, University of Basel
We present a protocol that permits to view and to quantitatively asses the morphology of the dendritic tree of individual Purkinje cells grown in organotypic cerebellar slice cultures. This protocol is intended to promote studies on the mechanisms of Purkinje cell dendritic development.
PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University
RNA transcripts are subject to extensive posttranscriptional regulation that is mediated by a multitude of trans-acting RNA-binding proteins (RBPs). Here we present a generalizable method to identify precisely and on a transcriptome-wide scale the RNA binding sites of RBPs.