The Journal of Visualized Experiments (JoVE) is a peer reviewed, PubMed-indexed video journal. Our mission is to increase the productivity of scientific research.

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Universität Basel

4 articles published in JoVE

 JoVE Immunology and Infection

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children


JoVE 3966 8/22/2012

1Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, 2University of Basel, Basel, Switzerland

Chronic infection with soil-transmitted helminths (STHs) causes malabsorption, stunting, and wasting in the growing child. Hence, it is plausible that these infections also reduce the physical fitness of children. Here, we visualize two techniques for the diagnosis of STHs and the 20-meter shuttle run test for assessing children's physical fitness.

 JoVE Neuroscience

A Functional Motor Unit in the Culture Dish: Co-culture of Spinal Cord Explants and Muscle Cells


JoVE 3616 4/12/2012

Biozentrum, University of Basel

Cultured muscle cells are an inadequate model to recapitulate innervated muscle in vivo. A functional motor unit can be reproduced in vitro by innervation of differentiated human primary muscle cells using rat embryo spinal cord explants. This article describes how co-cultures of spinal cord explants and muscle cells are established.

 JoVE Neuroscience

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures


JoVE 3637 3/21/2012

Anatomical Institute, Department of Biomedicine, University of Basel

We present a protocol that permits to view and to quantitatively asses the morphology of the dendritic tree of individual Purkinje cells grown in organotypic cerebellar slice cultures. This protocol is intended to promote studies on the mechanisms of Purkinje cell dendritic development.

 JoVE General

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins


JoVE 2034 7/02/2010

1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University

RNA transcripts are subject to extensive posttranscriptional regulation that is mediated by a multitude of trans-acting RNA-binding proteins (RBPs). Here we present a generalizable method to identify precisely and on a transcriptome-wide scale the RNA binding sites of RBPs.

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