Southern Research 1 article published in JoVE Immunology and Infection The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy Jennifer Chua1, Nathan A. Fisher2, Shane D. Falcinelli1, David DeShazer1, Arthur M. Friedlander3 1Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, 2Southern Research, 3Headquarters Division, United States Army Medical Research Institute of Infectious Diseases We present a protocol to utilize the Madagascar hissing cockroach as an alternative non-mammalian animal model to conduct bacterial virulence, pathogenesis, drug toxicity, drug efficacy, and innate immune response studies.
