The Bronx High School of Science 1 article published in JoVE Biology Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging Kelly Veerasammy*1,2, Yuki X. Chen*1,2, Sami Sauma*1, Mathilde Pruvost1, David K. Dansu1, Tenzin Choetso1,2, Tiffany Zhong3, Damien Marechal1, Patrizia Casaccia1, Rinat Abzalimov4,5, Ye He1,5 1The Graduate Center - Advanced Science Research Center, Neuroscience Initiative, The City University of New York, 2The City College of New York, CUNY, 3The Bronx High School of Science, 4The Graduate Center - Advanced Science Research Center, Structural Biology Initiative, The City University of New York, 5The Graduate Center - Advanced Science Research Center, MALDI MS Imaging Joint Core Facility, The City University of New York The goal of this protocol is to provide detailed guidance on the sample preparation when planning for experiments using MALDI MSI to maximize metabolic and molecular detection in biological samples.
