College of South Carolina 1 article published in JoVE Behavior Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms James Ingersoll1, Michael Moody1, Robert Holland1, Wesley Kuegler1, Charles Murrah Jr.1, John Winslow1, Neal Reynolds1, Nathaniel Lloyd1, Brian Dugan1, Madalyn Hammock1, Katherine Houlé2, Erin Clabough1 1Department of Biology, Hampden-Sydney College, 2College of Medicine at the Medical University of South Carolina, College of South Carolina This protocol measures spatial learning and memory using the Barnes maze. A novel Damsel-in-Distress paradigm is used to assess locomotor activity and prosocial behavior in mice.
