Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique

JoVE 3398 9/20/2011

Shrirang Karve^1,2, Michael E. Werner^1,2, Natalie D. Cummings^1,2, Rohit Sukumar^1,2, Edina C. Wang^1,2, Ying-Ao Zhang^1,2, Andrew Z. Wang^1,2

¹Laboratory of Nano- and Translational Medicine, Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, ²Carolina Center for Nanotechnology Excellence, University of North Carolina

This article describes a nanoprecipitation method to synthesize polymer-based nanoparticles using diblock co-polymers. We will discuss the synthesis of diblock co-polymers, the nanoprecipitation technique, and potential applications.