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Journal / Bioengineering / CometChip: En Højkapacitetsforskning 96-Well…
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Bioengineering

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CometChip: En Højkapacitetsforskning 96-Well platform til måling af DNA-skader i mikroarrayet humane celler

Article DOI: 10.3791/50607-v • 10:59 min • October 18th, 2014
October 18th, 2014 •
*1, *2, 3, 1, 1, 2, 2, 1
1Department of Biological Engineering, Massachusetts Institute of Technology, 2Environmental Toxicology, Chulabhorn Graduate Institute, 3Department of Biomedical Engineering, University of Minnesota
* These authors contributed equally

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Vi beskriver her en platform, der giver comet assay påvisning af DNA-skader med en hidtil uset overførselshastighed. Enheden mønstre pattedyr celler i en microarray og muliggør parallel behandling af 96 prøver. Den tilgang letter analysen af ​​basisniveau DNA-skader eksponering-induceret DNA-skader og DNA reparation kinetik.

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Bioengineering comet assay elektroforese microarray DNA-skader DNA-reparation
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