JoVE Journal
Medicine
Medicine
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
Summary
Established cancer cell lines and xenografts have been the mainstay of cancer research for the past several decades. However, recent evidence suggests that therapeutic response is greatly influenced by the tumor cell microenvironment. Therefore, we have developed an ex vivo analysis of primary tumor specimens for drug development purposes.