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JoVE Journal Bioengineering
Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles
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Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Article DOI: 10.3791/53099-v • 08:26 min • October 19th, 2015
October 19th, 2015 •
1, 2, 3, 4, 2,5, 1
1Division of Cardiovascular Diseases, Mayo Clinic, 2Division of Engineering, Mayo Clinic, 3School of Medicine, Pharmacy and Health, Durham University, 4Regional Center for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 5Mayo Clinic College of Medicine, Mayo Clinic

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Summary
Automatic Translation

Targeted cell delivery is useful in a variety of biomedical applications. The goal of this protocol is to use superparamagnetic iron oxide nanoparticles (SPION) to label cells and thereby enable magnetic cell targeting approaches for a high degree of control over cell delivery and localization.

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Cell Labeling Cell Targeting Superparamagnetic Iron Oxide Nanoparticles SPION Magnetic Cell Targeting Therapeutic Agents Biomedical Applications Targeted Delivery Magnetite Nanoparticles Poly(lactic-co-glycolic Acid) Coating Endocytosis Magnetic Fields Cell Sorting Biomedical Imaging Contrast Agent Drug Delivery Gene Delivery Diagnostic Assays Hyperthermia Therapy Tissue Soldering
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