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Neuroscience

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Implantation de la canule dans la Magna de Cisterna de rongeurs
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Implantation de la canule dans la Magna de Cisterna de rongeurs

Article DOI: 10.3791/57378
May 23rd, 2018 •
1, 1, 1, 1, 1,2, 3, 3,4, 1,3
1Center for Translational Neuromedicine, Division of Glial Therapeutics, University of Copenhagen, 2Department of Anesthesiology, Yale School of Medicine, 3Center for Translational Neuromedicine, Division of Glial Therapeutics, University of Rochester Medical Center, 4Department of Experimental Medical Science, Wallenberg Center for Molecular Medicine, Lund University

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May 23rd, 2018

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Nous décrivons ici un protocole pour effectuer une canulation cisterna magna (MCC), une façon mini-invasive pour livrer les traceurs, les substrats et les molécules de signalisation dans le liquide céphalo-rachidien (LCR). Combiné avec différentes modalités d’imagerie, CMc permet glymphatic système et évaluation dynamique CSF, ainsi que livraison de cerveau à l’échelle des divers composés.

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