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JoVE Journal Neuroscience
Bedömning av långvarig depression induktion hos vuxna cerebellär skivor
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Bedömning av långvarig depression induktion hos vuxna cerebellär skivor

Article DOI: 10.3791/59859-v • 09:30 min • October 16th, 2019
October 16th, 2019 •
1, 2
1Laboratory for Behavioral Genetics, Center for Brain Science, RIKEN, 2Senior Adviser's Office, Center for Brain Science, RIKEN

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I vissa genmanipulerade djur, med hjälp av ett enda protokoll kan misslyckas med att inducera LTD i cerebellär Purkinje celler, och det kan finnas en diskrepans mellan LTD och motoriskt lärande. Flera protokoll är nödvändiga för att bedöma LTD-induktion hos genmanipulerade djur. Standard protokoll visas.

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Neurovetenskap synaptisk plasticitet LTD Brain slice hel cells inspelning mus Purkinje cell cerebellum parallell fiber klättring fiber
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