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Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Article DOI: 10.3791/60727-v • 07:36 min • May 16th, 2020
May 16th, 2020 •
*1,2, *1,2, 1,2, 3, 1,2
1Laboratory of Novel Biologics, University of Virginia School of Medicine, 2Department of Biochemistry and Molecular Genetics, UVA Cancer Center, University of Virginia School of Medicine, 3Center for Comparative Medicine, University of Virginia
* These authors contributed equally

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Summary
Automatic Translation

Here we present a protocol to study the in vivo localization of antibodies in mice tumor xenograft models.

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Tumor Tissue Distribution Target Antigen Therapeutic Antibody Expression Purification Real-time Monitoring Screening Antibodies Non-specific Tissue Distribution Tumor Localization Quick And Cost-effective Technique Single-photon Emission Computed Tomography Positron Emission Tomography Radioactive Tracers Sophisticated Tracers Lung Diseases Heart Diseases Antibody Distribution Analysis Veterinary Technician CHO Cells Media DNA Cloning Polyethylenimine Stock
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