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Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
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Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Article DOI: 10.3791/61390-v • 08:42 min • July 3rd, 2020
July 3rd, 2020 •
*1, *2, 1, 1, 1, 1, 3, 1
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology, 2Department of Stomatology, Dalian Medical University, 3The 2nd Dental Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology
* These authors contributed equally

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Summary
Automatic Translation

This protocol describes a canonical method to understand the critical genes controlling osteoclast activity in vivo. This method uses a transgenic mouse model and some canonical techniques to analyze skeletal phenotype.

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Skeletal Phenotype Analysis Conditional Stat3 Deletion Mouse Model Genetically Engineered Mouse Models In Vivo Disease Mechanisms Skeletal Research Analyzing Skeletal Phenotype Animal Experiments High Quality Samples Dislocating Hip Joints Removing Skin From Hind Limb Articular Ligament Bone Immersion Paraffin Sectioning Micro CT Scanning Calcein And Alizarin Red Double Labeling Paraffin Sections
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