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GM-fri generation af blod-afledte neuronale celler
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GM-fri generation af blod-afledte neuronale celler

Article DOI: 10.3791/61634-v • 08:11 min • February 13th, 2021
February 13th, 2021 •
1, 1, 2, 2
1ACA CELL Biotech GmbH, 2Departmento Ciencias Biomedicas, Universidad Cardenal Herrera-CEU

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Vi præsenterer en genetisk modificeret-fri (GM-fri) metode til at opnå celler med en neuronal fænotype fra omprogrammerede perifere blodlegemer. Aktivering af en signalvej, der er knyttet til nyt humant GPI-forbundet protein, afslører en effektiv GM-fri metode til at opnå menneskelige pluripotente stamceller.

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Neurovidenskab Problem 168 Perifert blod omprogrammering signalering pluripotente stamceller neurale stamceller og celleerstatningsbehandlinger
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