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The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

Article DOI: 10.3791/61934-v • 07:55 min • April 14th, 2021
April 14th, 2021 •
1,2, 1,3, 1, 2,4, 1,2
1Department of Biology, American University, 2Center for Behavioral Neuroscience, American University, 3Department of Chemistry, American University, 4Department of Neuroscience, American University

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We present a behavioral chamber designed to assess cognitive performance. We provide data showing that once acquired, zebrafish remember the task 8 weeks later. We also show that hyperglycemic zebrafish have altered cognitive performance, indicating that this paradigm is applicable to studies assessing cognition and memory.

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Three-chamber Choice Task Zebrafish Model System Visual Discrimination Learning Cognitive Performance Zebrafish Mutants Drug Exposure Dr. Cassie Rowe Connaughton Laboratory Testing Chamber Aluminum U-shaped Channel Aquarium Three Chambers Opaque Dividers Gray PVC Sheets Beige Black White Felt Pieces Reward Adult Zebrafish Conspecifics Group Acclimation
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