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A Non-Invasive Method for Generating the Cyclic Loading-Induced Intra-Articular Cartilage Lesion Model of the Rat Knee

Article DOI: 10.3791/62660-v • 05:04 min • July 5th, 2021
July 5th, 2021 •
1, 2, 2, 2, 1, 2
1Department of Development and Rehabilitation of Motor Function, Human Health Sciences, Graduate School of Medicine, Kyoto University, 2Department of Motor Function Analysis, Human Health Sciences, Graduate School of Medicine, Kyoto University

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Summary
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Here, we present the cyclic loading-induced intra-articular cartilage lesion model of the rat knee, generated by 60 cyclic compressions over 20 N, resulting in damage to the femoral condylar cartilage in rats.

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Non-Invasive Method Cyclic Loading-Induced Intra-Articular Cartilage Lesion Model Rat Knee Cartilage Damage Animals Surgical Intervention Structured Destruction Fixation Device Anesthetized Rat Resin Concave Groove Hip Extension Knee Flexion Ankle Extension Stress And Tensile Testing Instrument Load Cell Calibration Button Frame Rotary Knob Preload Test Mode Compression Sensor Label
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