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JoVE Journal Cancer Research
Spontan murin model af anaplastisk kræft i skjoldbruskkirtlen
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Spontan murin model af anaplastisk kræft i skjoldbruskkirtlen

Article DOI: 10.3791/64607-v • 05:39 min • February 3rd, 2023
February 3rd, 2023 •
1, 1, 2, 3, 2, 4, 5, 1,6, 2,6
1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, 2Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital, Sichuan University, 3Department of Ultrasound, West China Hospital of Sichuan University, Sichuan University, 4Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center, University of Arizona, 5Center for Translational Medicine, Shenzhen Bay Laboratory, 6Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University

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Her præsenterer vi en standard pipeline til opnåelse af murine ATC-tumorer ved spontane genetisk manipulerede musemodeller. Endvidere præsenterer vi tumordynamik og patologisk information om de primære og metastaserede læsioner. Denne model vil hjælpe forskere med at forstå tumorigenese og lette lægemiddelopdagelser.

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Kræftforskning nr. 192
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