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Immunology and Infection

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JoVE Journal Immunology and Infection
Generering av en mus spontan autoimmun tyreoidit modell
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Generering av en mus spontan autoimmun tyreoidit modell

Article DOI: 10.3791/64609-v • 04:39 min • March 17th, 2023
March 17th, 2023 •
1,2, 1,2, 1,2, 3, 1
1Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, 2The Laboratory of Thyroid and Parathyroid Disease, West China Hospital of Sichuan University, 3State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center

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Flera typer av djurmodeller av Hashimotos tyreoidit har etablerats, liksom spontan autoimmun tyreoidit i NOD-musen. H-2h4-möss är en enkel och pålitlig modell för HT-induktion. Denna artikel beskriver detta tillvägagångssätt och utvärderar den patologiska processen för en bättre förståelse av SAT-murinmodellen.

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