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Journal / Genetics / Мышь in vivo Плацентарная манипуляция…
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Мышь in vivo Плацентарная манипуляция CRISPR
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Мышь in vivo Плацентарная манипуляция CRISPR

Article DOI: 10.3791/64760-v • 07:39 min • April 14th, 2023
April 14th, 2023 •
1,2,3, 2,3, 1,2,3,4
1Interdisciplinary Graduate Program in Genetics, University of Iowa, 2Department of Psychiatry, Carver College of Medicine, University of Iowa, 3Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, 4Hawk-IDDRC, University of Iowa

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Здесь мы описываем специфический по времени метод эффективного манипулирования критическими путями развития плаценты мыши in vivo. Это выполняется путем инъекции и электропорации плазмид CRISPR в плаценты беременных маток на эмбриональный день 12,5.

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Генетика выпуск 194 Плацента мышь CRISPR инсулиноподобный фактор роста 1 электропорация сверхэкспрессия развитие
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