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A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation
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A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

Article DOI: 10.3791/2096-v • 17:42 min • April 13th, 2011
April 13th, 2011 •
1, 1,2, 1,2,3
1Molecular and Cellular Biochemistry, Center for Molecular Neurobiology, The Ohio State University, 2Integrated Biomedical Science Graduate Program, The Ohio State University, 3Comprehensive Cancer Center, The Ohio State University

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Summary
Automatic Translation

Transplantation of isolated islets has been proposed to be a potential treatment for type 1 diabetes. Here we describe a method to isolate islets from mouse pancreata and transplant them to the subcapsular space of the kidney.

Tags

Islet Isolation Kidney Transplantation Type 1 Diabetes Islet Transplantation Blood Glucose Levels Immunosuppression Therapeutic Utility Mouse Kidney Capsule Surgical Steps Video Protocol Written Protocol Syngeneic Transplantation Allogeneic Transplantation
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