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Endothelin-1 induzierte Middle Cerebral Artery Occlusion Modell für ischämischen Schlaganfall mit Laser Doppler Flowmetrie Guidance in Rat
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Endothelin-1 induzierte Middle Cerebral Artery Occlusion Modell für ischämischen Schlaganfall mit Laser Doppler Flowmetrie Guidance in Rat

Article DOI: 10.3791/50014-v • 07:26 min • February 16th, 2013
February 16th, 2013 •
1, 2, 1, 3, 4, 4, 1, 3
1Department of Neurosurgery, University of Florida, 2Department of Anatomical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran, 3Department of Physiology and Functional Genomics, University of Florida, 4Department of Neurology, University of Florida

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Mehrere Tiermodelle von zerebraler Ischämie wurden entwickelt, um den menschlichen Zustand des Schlaganfalls simulieren. Dieses Protokoll beschreibt die Endothelin-1 (ET-1) induzierte mittlere Zerebralarterie (MCAO) Modell für ischämischem Schlaganfall bei Ratten. Darüber hinaus sind wichtige Erwägungen, Vorteile und Nachteile dieses Modells diskutiert.

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Medizin Neuroscience Neurobiologie Biomedical Engineering Chirurgie Anatomie Physiologie Erkrankungen des Nervensystems ischämische Schlaganfall Endothelin-1 zerebrovaskuläre Gehirn Arterie Schlaganfall Verschluss Laser doppley Flowmetrie Ratte Tiermodell
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