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Journal / Bioengineering / Combination of Microstereolithography and…
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Bioengineering

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JoVE Journal Bioengineering
Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration
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Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Article DOI: 10.3791/51826-v • 11:42 min • September 12th, 2014
September 12th, 2014 •
1, 1, 1, 1, 3, 2, 1, 1
1Department of Materials Science and Engineering, University of Sheffield, 2Department of Chemistry, University of Sheffield, 3L. V. Prasad Eye Institute

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Summary
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We report a technique for the fabrication of micropockets within electrospun membranes in which to study cell behavior. Specifically, we describe a combination of microstereolithography and electrospinning for the production of PLGA (Poly(lactide-co-glycolide)) corneal biomaterial devices equipped with microfeatures.

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Microstereolithography Electrospinning Membranes Niches Corneal Regeneration Corneal Disease Aniridia Steven Johnson Syndrome Chemical Burns Radiation Corneal Grafts Stem Cells Laboratory Expansion Carriers Amniotic Membrane Biomaterial Devices Physiological Environment Limbal Stem Cells Limbus Palisades Of Vogt Platform Technology Micropockets
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