Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biochemistry / An Efficient Method for the Synthesis of Peptoids …
JoVE Journal
Biochemistry

This content is Open Access.

JoVE Journal Biochemistry
An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity
DetectSyn: A Rapid, Unbiased Fluorescent Method to Detect Changes in Synapse Density
Journal (Biochemistry)
DetectSyn: A Rapid, Unbiased Fluorescent Method to Detect Changes in Synapse Density
Preparation of Chloroplast Sub-compartments from Arabidopsis for the Analysis of Protein Localization by Immunoblotting or Proteomics
Journal (Biochemistry)
Preparation of Chloroplast Sub-compartments from Arabidopsis for the Analysis of Protein Localization by Immunoblotting or Proteomics
 

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity

Article DOI: 10.3791/54750-v • 12:02 min • November 2nd, 2016
November 2nd, 2016 •
1, 2, 1
1Department of Chemistry, Durham University, 2School of Medicine, Pharmacy and Health, Durham University

Chapters

Summary
Automatic Translation

A protocol to synthesize peptoids with mixed cationic functionality in the same sequence is presented (lysine- and arginine-type monomers). Subsequent testing of these compounds against Leishmania mexicana, the protozoan parasites that cause cutaneous leishmaniasis, is also described.

Tags

Synthesis Peptoids Lysine-type Monomers Arginine-type Monomers Anti-leishmanial Activity Neglected Tropical Disease Cutaneous Leishmaniasis Therapeutics Cationic Functionality Biological Activities Mammalian Form Of The Parasite Insect Stage Leishmania Mexicana Synthesis Protocol Dimethylformamide Fmoc-protected Rink Amide Resin
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter