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Biology

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Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction
 

Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction

Article DOI: 10.3791/708-v 05:29 min March 17th, 2008
March 17th, 2008

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Summary

The hair follicle is a highly complex appendage of the skin containing a multiplicity of cell types. The follicle undergoes constant cycling through the life of the organism including growth and resorption with growth dependent on specific stem cells. The targeting of the follicle by genes and stem cells to change its properties, in particular, the nature of the hair shaft is, discussed. Hair follicle delivery systems are described, such as liposomes and viral vectors for gene therapy. The nature of the hair follicle stem cells is discussed, in particular, its pluripotency.

Tags

Hair Follicle GFP Ex Vivo Viral Transduction Cell Types Hair Matrix Cells Stem Cells Anagen Pluripotent Stem Cells Gene Therapy Gene Delivery System Viral Vectors Liposomes Gene Targeting
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