From Polyp to Metastatic Cancer

Tumor progression is the stepwise change that can turn an early tumor into a more aggressive and malignant cancer. Foulds first described this pattern in the 1950s. Colon cancer is one of the best-known examples, because researchers can follow its changes over time.

In colon cells, an early mutat...

Tumor progression is a phenomenon where the pre-formed tumor acquires successive morphological and molecular changes to become more aggressive and malignant in its  character.

Cancer begins as a single genetic change in a healthy cell, and with time, the progenies of that cell continue to proliferate and pass on the mutation to all the da...