Name: vertical and horizontal gene transfer
Uploaded: 2023-04-30T18:28:42.000Z
Duration: 2 min 18 s
Channel: JoVE

K12 Standards

north-carolina-k-12-science-standard-course-of-study

North Carolina K-12 Science Standard Course of Study

9-12

Biology

heredity-inheritance-and-variation-of-traits

Heredity- Inheritance and Variation of Traits

LS.Bio.6.2

types-of-genetic-transfer-between-organisms

Types of Genetic Transfer Between Organisms

يحدث نقل جينى عندما تكون المعلومات الجينية منقولة من كائن حي إلى آخر. هناك نوعان من النقل الجينى،رأسي وأفقي. النقل الجينى الرأسي،الأكثر شيوعاًبين الاثنين،هو انتقال المعلومات الوراثية من جيل واحد 00:00:20.400 00:00:22.320 إلى التالي.يحدث النقل الجينى العمودي في الكائنات الحية التى تتكاثر جنسيا حيث يمر تقريبا نصف دى إن أيه إلى الأبناء 00:00:30.350 00:00:33.660 وفي الكائنات الحية التى تتكاثر لاجنسيا والتى تنتج ذرية متطابقة وراثيا. النقل الجينى الأفقى على العكس من ذلك،يحدث عندما تكون المادة الوراثية من كائن حي قد أ دخلت لكائن حي آخر فى نفس الجيل. في حالة بعض انواع بدائيات النوى مثل البكتيريا،يحدث نقل افقى للجين بين الأنواع المختلفة.النقل الافقى للجين فى بدائيات النوى يحدث عبر ثلاث آليات،التحول،الدمج،والتوافق. في التحول،الخلية بدائية النواة تأخذ الدى ان ايه المجرد(بدون الهيستون)من البيئة. أثناء عملية الدمج،الفيروسات و الفيروسات البكتيرية(العاثيات)في هذا المثال،تحلل دى إن إيه فى الخلية المضيفة لهم.الأطوال الصغيرة من الحمض النووي المضيف يمكن تعبئتها في سلالة من البكتريوفاج قبل أن تتحلل الخلية المضيفة. ثم تستمر السلالة الفيروسية فى إصابة المزيد من الخلايا البكتيرية،وبالتالي تصبح هذه السلالة وسيط غير متعمد للنقل بطريقة الدمج. في المرافقة،دى إن أيه يتم نقله مباشرة من خلية إلى آخرى عبر بنية تسمى الشعرة الإخصابية.على الرغم من ان المرافقة هى شكل من أشكال التزاوج إلا انه بالنسبة للكائنات لا جنسية التكاثر لا يعتبر تزاوج جنسي حقيقى لأنه لا توجد أمشاج متبادلة أو نسل تم إنتاجه. وكل من هذه الآليات يمكن ملاحظتها في الطبيعة ولها تطبيقات معملية. على سبيل المثال،يمكن استخدام الترافق لمنح مقاومة المضادات الحيوية من سلالة بكتيرية إلى آخرى،مانحة بذلك سلالة 00:02:13.510 00:02:17.370 يمكن أن تكون مقاومة لمضادّات حيويّة متعددة.

<ol>
	<li>Arber W. نقل الجينات الأفقي بين البكتيريا ودورها في التطور البيولوجي. الحياة (بازل). 2014; 4(2):217–224. تم النشر في 2014 مايو 16. دوي: 10.3390 / life4020217</li>
	<li>بويجبو ، بيري ، يوري آي وولف ، ويوجين ف. كونين. "ابحث عن" شجرة الحياة "في غابة النشوء والتطور". مجلة علم الأحياء 8.6 (2009): 59.</li>
</ol>

أنواع النقل الجيني بين الكائنات الحية

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يحدث النقل الوراثي عندما تنتقل المعلومات الوراثية من كائن حي إلى آخر. ويحدث عبر آليتين: نقل الجينات العمودي ونقل الجينات الأفقي. يحدث نقل الجينات العمودي عندما يتم نقل المعلومات الوراثية من جيل إلى جيل، وهو ما يحدث بشكل متكرر أكثر بكثير من نقل الجينات الأفقي. يعد كل من التكاثر الجنسي واللاجنسي أحد أشكال نقل الجينات العمودي، حيث يمرر كائن حي أو أكثر بعض أو كل الجينوم الخاص به إلى ذريته. بالإضافة إلى ذلك، يحدث نقل الجينات العمودي في كل من الأنواع بدائية النواة وحقيقية النواة.

يحدث نقل الجينات الأفقي عندما يتم تمرير المعلومات الوراثية إلى عضو من نفس الجيل ويحدث في أغلب الأحيان في الأنواع بدائية النواة. في حين أن النقل الجيني الأفقي بين الأنواع نادر للغاية بين حقيقيات النوى، فإنه يحدث بشكل متكرر في بدائيات النوى. يعد نقل الجينات الأفقي بين الأنواع المختلفة مصدرًا مهمًا للتنوع الجيني بين بدائيات النوى.

تتكاثر معظم الأنواع بدائية النواة لا جنسيًا. في حين أن هذا يسمح بإنتاج النسل بشكل أسرع، فإن النسل المنتج يمتلك تنوعًا جينيًا محدودًا. وبالتالي، فإن نقل الجينات الأفقي يلعب دورًا حيويًا في إدخال التنوع الجيني إلى بدائيات النوى. من خلال نقل الجينات الأفقي، يمكن لبدائيات النوى مشاركة جزء صغير من الجينوم الخاص بها مع كائنات حية أخرى، إما محددة (نفس النوع) أو غير محددة (نوع مختلف)، في نفس الجيل. يفترض العديد من العلماء أن النقل الجيني الأفقي والطفرات هما أهم مصادر التباين الوراثي في بدائيات النوى. وهكذا، فإن نقل الجينات الأفقي يوفر بعض المواد الخام التي يعمل عليها الاصطفاء الطبيعي.

ومن الأمثلة البارزة على ذلك ظهور سلالات من البكتيريا المقاومة للمضادات الحيوية. يمكن للجينات التي تمنح المقاومة للمضادات الحيوية أن تنتقل بين أنواع وسلالات مختلفة من البكتيريا، مما يمنح البكتيريا المتلقية ميزة انتقائية، مثل سلالات النيسرية البنية المقاومة للبنسلين، والتي تسبب مرض السيلان. وعلى نطاق أوسع، تشير بعض التقديرات إلى أن ما لا يقل عن 18% من جينوم الإشريكية القولونية تم الحصول عليه عن طريق النقل الجيني الأفقي على مدار ملايين السنين من التطور.

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يحدث النقل الجيني عندما تنتقل المعلومات الجينية من كائن حي إلى آخر. يحدث عبر آليتين: نقل الجينات الرأسي و ...

Education

JoVE Core

Cell Biology

بيولوجيا الخلية

Unit 1

الوحدة الأولى

Cells, Genomes, and Evolution

الخلايا والجينومات والتطور

KEY TERMS AND CONCEPTS

المصطلحات والمفاهيم الأساسية

vertical and horizontal gene transfer

Genetic transfer between organisms happens in two main ways: vertical gene transfer and horizontal gene transfer. These two routes explain how hereditary material moves from one generation to the next or between organisms that are not parent and offspring.

Vertical gene transfer passes genes from parent to offspring during reproduction. This is the usual way genetic information is inherited in living things.

Horizontal gene transfer moves genetic material between organisms outside of reproduction. It can occur between unrelated organisms and helps explain how genes may spread in a population. Together, these transfer types show different paths that DNA can take between organisms.

Vertical and Horizontal Gene Transfer

what are cells?

Cells as the Building Blocks of Life

Cells are the basic building blocks of life. A bacterium can be a single cell, while a human is made of trillions of cells. Even with this range, cells share key features that support life. A living cell has a plasma membrane. This is a bilayer of lipids that separates the cytoplasm inside the cell from the outside environment. A cell also carries genetic information in the form of DNA. In prokaryotic cells, DNA is found in a region called the nucleoid. In eukaryotic cells, DNA is enclosed...

the tree of life - bacteria, archaea, and eukaryotes

the-tree-of-life-bacteria-archaea-and-eukaryotes

Three Domains on the Tree of Life

The tree of life shows how living things are grouped into three domains: Bacteria, Archaea, and Eukaryotes. This classification helps explain the major branches of life and how they are related. Bacteria and Archaea are both single-celled organisms, but they are not the same. Eukaryotes include organisms with more complex cells, such as plants, animals, and fungi. Together, these three domains give a broad picture of life on Earth. Understanding the tree of life helps students compare cell...

prokaryotic cells

How Prokaryotes Survive Without a Nucleus

Prokaryotes are small unicellular organisms that live without a nucleus. They include the domains Archaea and Bacteria. Bacteria include common microbes such as Salmonella and E. coli, while Archaea include extremophiles that live in harsh places like volcanic springs. Prokaryotic cells still share several basic features with eukaryotic cells. They have a plasma membrane, cytoplasm, ribosomes, and genetic material in the form of single, circular DNA. Their cell parts float freely in the...

eukaryotic compartmentalization

How Organelles Keep Cells Working

Eukaryotic cells keep their organelles separate so each part can do a specific job. Organelles such as the nucleus and mitochondria are surrounded by membranes. These membranes are selectively permeable, which means they control what enters and leaves. That control creates small internal environments with conditions suited to each organelle. These controlled spaces help organelles work more efficiently. In animal cells, lysosomes keep an acidic environment that helps their enzymes digest...

eukaryotic evolution

How Eukaryotic Cells Became Complex

Eukaryotic cells became complex through a debated evolutionary path that likely involved endosymbiosis. The most accepted model is the endosymbiont theory, which explains how organelles such as mitochondria and chloroplasts may have entered an ancestral cell. Other ideas include the nucleus-first hypothesis, the mitochondria-first hypothesis, and the eukaryote-first hypothesis. The nucleus-first hypothesis says an ancestral prokaryote first formed a membrane around its DNA, creating the...

animal and plant cell structure

Plant vs Animal Cell Division and Specialization

Plant and animal cells differ in how they divide, organize into tissues, and specialize for different jobs. Both cell types divide by mitosis in non-gametic cells and by meiosis in gametic cells, but the details are not the same. These differences help explain how each cell type supports growth and reproduction. During cell division, animal cells use centrosomes to organize spindle fibers and separate chromosomes. Plant cells do not have centrosomes. Instead, they use a microtubule-organizing...

cytoplasm

Cytoplasm and the Cell’s Internal Support

The cytoplasm is the cell’s internal space that holds organelles and the cytoskeleton. It is suspended in the cytosol, an aqueous fluid made of water, ions, salts, and many organic molecules. This fluid helps keep the cell organized and supports many cellular activities. The cytoplasm is also where protein synthesis and protein folding take place. The watery cytosol helps proteins fold correctly. In a folded protein, hydrophobic amino acid side chains tend to stay buried in the core, while...

the nucleus

Nuclear DNA, Chromatin, and Nucleoli

The nucleus is a membrane-bound organelle that stores chromosomal DNA and helps control what proteins a eukaryotic cell makes. It acts as the cell’s control center. DNA in mitochondria and chloroplasts is different because it mainly supports functions specific to those organelles. Inside the nucleus, DNA is wrapped around proteins called histones. This DNA-protein complex is called chromatin. During interphase, when the cell is not dividing, chromatin stays loosely arranged so the DNA is easy...

the dna helix

How DNA Structure Was Discovered

DNA is the genetic material that passes traits from one generation to the next in organisms and most viruses. It is made of two strands of nucleotides that twist into a spring-like double helix. The shape is not perfectly even. It also has repeating grooves called the major groove and the minor groove. The major groove forms where the sugar-phosphate backbones are farther apart. This wider space gives DNA-binding proteins, including transcription factors, better access to the bases. The minor...

the central dogma

DNA to Protein: RNA’s Role

DNA to protein flow depends on RNA as the link between genetic information and the amino acids that build proteins. Early scientists knew that DNA stores the information for cell functions and that proteins carry out most of those functions. For a long time, they did not know how the code in DNA became a working protein. At first, many people thought one gene was changed directly into its protein. Two findings in eukaryotic cells challenged that idea. Protein production does not happen in the...

mutations

Mutations in DNA and Inherited Disease

Mutations are changes in the DNA sequence. They can happen on their own during DNA copying, or they can be caused by environmental factors. Scientists describe mutations in several ways, including whether they change the amino acid sequence of a protein, how much DNA they affect, and whether they occur in somatic cells or germline cells. Some mutations are point mutations. A point mutation changes a single nucleotide in DNA. Other mutations are chromosomal alterations, which change the number...

genome size and the evolution of new genes

genome-size-and-the-evolution-of-new-genes

Genome Size and Gene Evolution

Genome size and gene evolution are linked through changes in DNA sequence and genome structure. Some genes can arise from parts of the genome that were not coding before, while others come from changes to existing genes. These shifts help explain how new genetic material can appear over time. A genome is the full set of DNA in an organism. Its size can change as DNA is added, removed, or rearranged. The transcript highlights that genome size is not fixed, and that these changes can shape the...

gene families

Shared Origins of Gene Families

Gene families are groups of related genes that share a common origin. They form when genes are copied and then change over time. These related genes can be found within the same genome. The video also connects gene families to homologous genes and orthologous genes. Homologous genes are genes with a shared evolutionary origin. Orthologous genes are homologous genes found in different species. Gene families help show how these relationships are used to study evolution and related gene functions.

gene evolution - fast or slow?

Gene Evolution Rates and Selection

Gene evolution can happen at different rates, and natural selection helps shape those changes. Some genes change slowly because important DNA changes are removed over time. Other genes can change more quickly when different mutations are kept in a population. The rate of evolution depends on how a gene is used and how strongly it is affected by selection. Genes with essential jobs often stay more similar across species. Genes under weaker pressure may show more variation and may evolve faster.<br...

types of genetic transfer between organisms

Genetic transfer between organisms happens in two main ways: vertical gene transfer and horizontal gene transfer. These two routes explain how hereditary material moves from one generation to the next or between organisms that are not parent and offspring. Vertical gene transfer passes genes from parent to offspring during reproduction. This is the usual way genetic information is inherited in living things. Horizontal gene transfer moves genetic material between organisms outside of...

key terms and concepts

Explore the two main ways genetic material moves between organisms: vertical gene transfer from parent to offspring and horizontal gene transfer between unrelated organisms.

Vertical and Horizontal Gene Transfer | JoVE K12

cell biology

JoVE Core Cell Biology illustrates complex cellular processes in easy-to-understand yet comprehensive animated video lessons. This collection focuses on the essential components and functions of cells, including organelles and membranes, cellular transport, and cell energetics. It is complemented by scientist-in-action videos that demonstrate the application of cell biology in real-world research experiments.

Pennsylvania State Academic Standards

Life Science

Inheritance and Variation of Traits

3.1.9-12.Q

Louisiana Student Standards for Science

High School

Life Sciences

Biological Evolution: Unity And Diversity

HS-LS4-1

ohios-learning-standards-and-model-curriculum

Ohio’s Learning Standards and Model Curriculum

Heredity

Mutations

Virginia  Standards of Learning

HIgh School

BIO.5

BIO.5.b

Next Generation Science Standards

Heredity: Inheritance and Variation of Traits

HS-LS3-2

new-york-state-science-learning-standards

New York State Science Learning Standards

HS-LS3-1.

What is Meiosis?

Meiosis is the process by which diploid cells divide to produce haploid daughter cells. In humans, each diploid cell contains 46 chromosomes, half from ...

Meiosis I

Meiosis II

Meiosis vs. Mitosis

Crossing Over

Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to ...

Nondisjunction

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This ...

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of ...

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from ...

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ...

Cleavage and Blastulation

After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage ...

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of ...

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three ...

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms ...

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. ...

Use models to explain how DNA is passed from parents to offspring through the processes of meiosis and fertilization in sexual reproduction.

LS.Bio.6.1

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations ...

Genome Size and the Evolution of New Genes

Base-pairing and DNA Repair

The DNA Replication Fork

Lagging Strand Synthesis

The Replisome

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template ...

Replication in Prokaryotes

DNA replication has three main steps: initiation, elongation, and termination. Replication in prokaryotes begins when initiator proteins bind to the ...

Replication in Eukaryotes

In eukaryotic cells, DNA replication is highly conserved and tightly regulated. Multiple linear chromosomes must be duplicated with high fidelity before ...

Overview of DNA Repair

Base Excision Repair

Nucleotide Excision Repair

DNA Distortion and Damage
Cells are regularly exposed to mutagens&#8212;factors in the environment that can damage DNA and generate mutations. UV ...

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the ...

Fixing Double-strand Breaks

Homologous Recombination

Gene Conversion

Restarting Stalled Replication Forks

Construct an explanation to summarize how inheritable genetic variations may result from: new genetic combinations in meiosis, mutations during replication, or mutations caused by environmental factors.

An Overview of Genetic Analysis

An organism&#8217;s physical traits, or phenotype, are a product of its genotype, which is the combination of alleles (gene variants) inherited from its ...

Genetic Crosses

To dissect genetic processes or create organisms with novel suites of traits, scientists can perform genetic crosses, or the purposeful mating of two ...

Punnett Squares

Monohybrid Crosses

Dihybrid Crosses

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel&#8217;s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A ...

Law of Independent Assortment

Chi-square Analysis

The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an ...

Pedigree Analysis

Multiple Allele Traits

Incomplete Dominance

Gregor Mendel&#39;s work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid ...

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cu&#233;not discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is ...

Polygenic Traits

background-and-environment-affect-phenotype

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as ...

Use mathematics and computational thinking to predict the variation and distribution of expressed traits based on: Mendelian inheritance, co-dominance, incomplete dominance, multiple alleles, and sex-linked inheritance.

LS.Bio.7.1

Overview

A pedigree is a diagram displaying a family&#x2019;s history of a trait. Analyzing pedigrees can reveal (1) whether a trait is dominant or ...

Probability Laws

Overview

The probability of inheriting a trait can be calculated using the sum and product rules. The sum rule is used to calculate the probability of ...

The Concept of Multiple Allelism

Multiple allelism describes genes that exist in three or more allelic forms. Although diploid organisms, like humans, ...

Analyze and interpret data to explain how polygenic traits result in a wide range of phenotypes.

LS.Bio.7.2

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause ...

Nature and Nurture

Many human characteristics, like height, are shaped by both nature&mdash;in other words, by our genes&mdash;and by nurture, or our environment. For ...

Construct an explanation to summarize how traits result from interactions of genetic factors (multiple genes and/or alleles) and environmental factors.

LS.Bio.7.3

PCR: The Polymerase Chain Reaction

The polymerase chain reaction, or PCR, is a technique used to amplify DNA through thermocycling &#8211; cyles of temperature changes at fixed time ...

DNA Gel Electrophoresis

DNA gel electrophoresis is a technique used for the detection and separation of DNA molecules. An electric field is applied to a gel matrix comprised of ...

DNA Isolation

DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further ...

Restriction Enzymes

Restriction enzymes are bacterial enzymes used to cut DNA in a sequence-specific manner. To cleave DNA, they bind to specific palindromic sequences called ...

DNA Agarose Gel Electrophoresis

Agarose gel electrophoresis is a laboratory technique commonly used to separate DNA fragments by size. However, it can also be used to isolate and purify ...

dna-isolation-and-restriction-enzyme-analysis

DNA Isolation and Restriction Enzyme Analysis

The revelation of DNA as the hereditary molecule in all organisms has led to enormous scientific and medical breakthroughs and significantly enhanced our ...

Analyze and interpret data to compare DNA samples.

LS.Bio.8.1

Understand genetic mechanisms for variation.

Vertical and Horizontal Gene Transfer

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