Mechanical Failure

Mechanical failure is the loss of a component’s ability to safely support loads or perform its intended function, often resulting from excessive stress, deformation, fracture, wear, or material degradation. It occurs when applied forces exceed a material’s strength or when repeated loading initiates and propagates fatigue cracks; instability such as buckling can also cause sudden failure. In bioengineering, analyzing mechanical failure helps assess implants, prostheses, tissue-engineering scaffolds, and medical devices exposed to physiological forces and environments. Failure analysis guides material selection, structural design, testing, and safety improvements, supporting more durable devices and reducing risks to patients.

Mechanical Failure - Related Videos

Research

JoVE Journal - Engineering

Imaging of the Microstructural Failure Mechanism in the Human Hip

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Cited by 1 •

2023

The protocol enables the measurement of the deformation of the bone microstructure in the entire proximal human femur and its toughness by combining large-volume micro-CT scanning, a custom-made compressive stage, and advanced image processing tools.

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

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Cited by 1 •

2015

The time-dependent dielectric breakdown (TDDB) in on-chip interconnect stacks is one of the most critical failure mechanisms for microelectronic devices. This paper demonstrates the procedure of an in situ TDDB experiment in the transmission electron microscope, which opens a possibility to study the failure mechanism in microelectronic products.

A Virtual Simulation Experiment of Mechanics: Material Deformation and Failure Based on Scanning Electron Microscopy

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2023

This work presents a three-dimensional virtual simulation experiment for material deformation and failure that provides visualized experimental processes. Through a set of experiments, users can become familiar with the equipment and learn the operations in an immersive and interactive learning environment.

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

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Cited by 21 •

2011

A method of gene transfer for the treatment of ischemic heart failure is described using a swine model of myocardial infarction. Our simple and reproducible method enables us to readily evaluate the efficacy of various gene transfers with a very simple and reproducible way.

Humor or Rationality? The Neural Mechanisms of How Agent Type and Language Style Influence Satisfaction with Ride-Hailing Service Failure Recovery

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2026

This study employs ERPs to investigate how agent type (human/AI) and language style (humorous/rational) influence ride-hailing service recovery satisfaction, aiming to uncover neurocognitive mechanisms.

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