Ultrafast Pulses

Ultrafast pulses are extremely brief bursts of electromagnetic energy, typically generated by lasers, that deliver energy over femtosecond-to-picosecond timescales; their short duration produces very high peak intensities while limiting heat diffusion. In bioengineering, a focused pulse can induce nonlinear absorption, such as multiphoton excitation, so energy is deposited only where photon density is sufficiently high, enabling three-dimensional spatial control with reduced damage outside the focal region. This principle supports multiphoton microscopy, precision microsurgery, photopolymerization, and biomaterial processing. Controlling pulse duration, wavelength, repetition rate, and fluence helps researchers tune imaging contrast, fabrication accuracy, and tissue response.

Ultrafast Pulses - Related Videos

Education

JoVE Core - Anatomy and Physiology

Pulse

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2024

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level. The pulse serves as a clinical indicator...

Pulse

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2024

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action. Pulse Rate and its Significance Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...

Research

JoVE Journal - Bioengineering

Blood Flow Imaging with Ultrafast Doppler

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Cited by 10 •

2020

This protocol shows how to apply ultrafast ultrasound Doppler imaging to quantify blood flows. After a 1 s long acquisition, the experimenter has access to a movie of the full field of view with axial velocity values for each pixel every ≈0.3 ms (depending on the ultrasound time of flight).

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

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2024

A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.

Regulation of Pulse

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2024

Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state. Autonomic Nervous System, or ANS: ANS regulates heart rate and pulse involuntarily through the sinoatrial node, the heart's pacemaker. The sympathetic branch speeds up the pulse rate during stress or physical activity by releasing norepinephrine. The...

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