Bioaccumulation

Bioaccumulation is the gradual buildup of a chemical substance within an organism when uptake from the environment or food exceeds its ability to metabolize and eliminate it. Hydrophobic, persistent compounds can be stored in lipid-rich tissues, allowing concentrations to rise over time even when surrounding levels remain low. In biology, studying bioaccumulation helps researchers assess how pollutants move through organisms, affect physiological processes, and threaten individual and population health. Measurements of tissue concentrations support environmental monitoring, contaminant-risk assessment, and evaluation of aquatic and terrestrial ecosystems, while also clarifying how exposure duration, chemical properties, and organism biology shape toxic effects.

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Research

JoVE Journal - Developmental Biology

Salinity-dependent Toxicity Assay of Silver Nanocolloids Using Medaka Eggs

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2016

Embryonic stages are the most susceptible to xenobiotics. Although chemical toxicity depends on salinity, no method exists to test the salinity dependence of toxicity to aquatic organisms. Here, we describe a new and high-throughput method for determining the salinity dependence of toxicity to aquatic embryos.

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