Central Vein

The central vein is a blood vessel positioned within the center of a tissue or organ, where it collects blood from smaller vessels and directs it toward larger veins. In a classic liver lobule, blood flows through hepatic sinusoids from the portal triads toward the central vein, allowing hepatocytes to exchange substances with blood before it leaves the lobule through the hepatic venous system. Studying central vein structure and blood flow helps students and researchers understand liver organization, oxygen and nutrient gradients, and the effects of conditions such as congestion, fibrosis, or impaired circulation on tissue function.

Central Vein - Related Videos

Education

JoVE Science Education - Clinical Skills

Central Venous Catheter Insertion: Subclavian Vein

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations for hemodynamic monitoring, medication delivery, and blood sampling. There are three veins in the body that are accessed for central venous cannulation: the internal jugular, the subclavian, and the femoral vein. Central venous access via the subclavian vein has several advantages over other possible locations. The subclavian...

Central Venous Catheter Insertion: Femoral Vein

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations, including vascular access, vasopressor and caustic medication delivery, central venous pressure monitoring, volume resuscitation, total parental nutrition, hemodialysis, and frequent phlebotomy. There are three veins in the body that are accessed for central venous cannulation: the internal jugular, the subclavian, and the...

Research

JoVE Journal - Medicine

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

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2025

We present a laparoscopic technique for anatomic S7+S8d resection with right hepatic vein transection, preserving the inferior right hepatic vein and segment S6. Relying on meticulous anatomical landmarks without intraoperative ultrasound, this approach offers a precise and parenchyma-sparing option for dorsally located right-liver tumors, particularly in settings with limited advanced navigation resources.

Central Venous Catheter Insertion: Internal Jugular

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations, including vascular access, vasopressor and caustic medication delivery, central venous pressure monitoring, intravascular device delivery (pacing wires, Swann-Ganz catheters), volume resuscitation, total parental nutrition, hemodialysis, and frequent phlebotomy. Safe reliable placement of a central venous catheter (CVC) in...

Measures of Central Tendency

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2020

The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians, "average" is commonly accepted for "arithmetic mean." Another measure of...

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