Iron Cycling

Iron cycling is the movement and transformation of iron among biological, geological, and chemical reservoirs, making it important for nutrient availability and ecosystem function. In soils, sediments, and aquatic environments, iron shifts between reduced ferrous iron and oxidized ferric iron through redox reactions influenced by oxygen, pH, organic matter, and microbial activity; these changes also control whether iron dissolves, precipitates, or binds to minerals. Organisms use iron in enzymes, electron transport, and metabolism, while iron minerals can immobilize or release phosphorus and other elements. Studying iron cycling helps explain biogeochemical processes, microbial ecology, water quality, and nutrient dynamics in changing environments.

Iron Cycling - Related Videos

Research

JoVE Journal - Biology

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

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Cited by 3 •

2022

This article demonstrates how to prepare and administer transferrin-bound nonradioactive isotopic iron for studies of iron transport in mouse pregnancy. The approach for quantifying isotopic iron in fetoplacental compartments is also described.

Culturing Mycobacterium tuberculosis Under Iron-Limited Conditions

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2025

Source: Gupta, S., et al. Isolation and Characterization of Extracellular Vesicles Produced by Iron-limited Mycobacteria. J. Vis. Exp. (2019)This video demonstrates the procedure for culturing Mycobacterium tuberculosis under iron-limited conditions to induce iron stress and promote the secretion of siderophores that support bacterial survival.

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source

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Cited by 31 •

2013

Here we describe a growth assay for Staphylococcus aureus using hemoglobin as the sole source of available nutrient iron. This assay establishes the role of bacterial factors involved in hemoglobin-derived iron acquisition.

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

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Cited by 9 •

2022

Here, a protocol for the measurement of the non-heme iron content in animal tissues is provided, using a simple, well-established colorimetric assay that can be easily implemented in most laboratories.

Education

JoVE Core - Biology

What are Biogeochemical Cycles?

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2019

The most common elements in organic molecules, carbon, hydrogen, oxygen, nitrogen, sulfur, and phosphorus, are only available in the ecosystem in limited amounts. Therefore, these nutrients must be recycled through both biotic and abiotic components of the ecosystem, in processes generally called biogeochemical cycles. Biogeochemical Cycles and Decomposition The matter that makes up living organisms, like water, carbon, nitrogen, sulfur and phosphorous, exist in limited quantities within the...

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